Detailed information NTG1083365

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: ACLINZ_RS20575
• Genome accession: NZ_CP176860
• Coordinates: 3988268..3989062 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus thuringiensis strain MPB18
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 3983268..3994062

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLINZ_RS20555 (ACLINZ_20555)	-	3985069..3985302 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
ACLINZ_RS20560 (ACLINZ_20560)	-	3985351..3986079 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
ACLINZ_RS20565 (ACLINZ_20565)	-	3986130..3986276 (+)	147	WP_001247671.1	YycC family protein	-
ACLINZ_RS20570 (ACLINZ_20570)	-	3986444..3987970 (-)	1527	WP_000218390.1	glycosyltransferase family 39 protein	-
ACLINZ_RS20575 (ACLINZ_20575)	spo0A	3988268..3989062 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
ACLINZ_RS20580 (ACLINZ_20580)	spoIVB	3989350..3990648 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
ACLINZ_RS20585 (ACLINZ_20585)	recN	3990767..3992506 (-)	1740	WP_000947757.1	DNA repair protein RecN	Machinery gene
ACLINZ_RS20590 (ACLINZ_20590)	argR	3992774..3993223 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=1083365 ACLINZ_RS20575 WP_003161566.1 3988268..3989062(-) (spo0A) [Bacillus thuringiensis strain MPB18]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=1083365 ACLINZ_RS20575 WP_003161566.1 3988268..3989062(-) (spo0A) [Bacillus thuringiensis strain MPB18]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818