Detailed information NTG1082612

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACK2V1_RS00450
• Genome accession: NZ_CP176715
• Coordinates: 100708..101595 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain GTVSS-007
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 95708..106595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACK2V1_RS00420 (ACK2V1_00420)	-	96440..97201 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
ACK2V1_RS00425 (ACK2V1_00425)	-	97446..97901 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACK2V1_RS00430 (ACK2V1_00430)	-	98023..98124 (+)	102	WP_000731976.1	SE2200 family small protein	-
ACK2V1_RS00435 (ACK2V1_00435)	-	98184..99608 (-)	1425	WP_000953755.1	alkaline phosphatase	-
ACK2V1_RS00440 (ACK2V1_00440)	-	99806..100006 (+)	201	WP_000604730.1	hypothetical protein	-
ACK2V1_RS00445 (ACK2V1_00445)	braR	100032..100697 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACK2V1_RS00450 (ACK2V1_00450)	braS	100708..101595 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACK2V1_RS00455 (ACK2V1_00455)	-	101703..102458 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACK2V1_RS00460 (ACK2V1_00460)	-	102455..104455 (+)	2001	WP_099130585.1	ABC transporter permease	-
ACK2V1_RS00465 (ACK2V1_00465)	-	105114..105227 (+)	114	Protein_92	hypothetical protein	-
ACK2V1_RS00470 (ACK2V1_00470)	-	105609..105869 (+)	261	WP_001791974.1	hypothetical protein	-
ACK2V1_RS00475 (ACK2V1_00475)	-	105879..106376 (+)	498	WP_001065268.1	glutathione peroxidase	-
ACK2V1_RS00480 (ACK2V1_00480)	-	106484..106576 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1082612 ACK2V1_RS00450 WP_000143425.1 100708..101595(+) (braS) [Staphylococcus aureus strain GTVSS-007]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1082612 ACK2V1_RS00450 WP_000143425.1 100708..101595(+) (braS) [Staphylococcus aureus strain GTVSS-007]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1