Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACK2VV_RS09915 Genome accession   NZ_CP176712
Coordinates   2013694..2014413 (+) Length   239 a.a.
NCBI ID   WP_409530657.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GTVSS-008     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2008694..2019413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2VV_RS09885 (ACK2VV_09885) - 2008915..2009541 (+) 627 WP_000522381.1 nitroreductase family protein -
  ACK2VV_RS09890 (ACK2VV_09890) - 2009902..2010687 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  ACK2VV_RS09895 (ACK2VV_09895) hld 2011287..2011367 (-) 81 WP_000046022.1 delta-hemolysin -
  ACK2VV_RS09900 (ACK2VV_09900) - 2011657..2012220 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  ACK2VV_RS09905 (ACK2VV_09905) agrD 2012223..2012366 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  ACK2VV_RS09910 (ACK2VV_09910) agrC 2012396..2013679 (+) 1284 WP_099112243.1 quorum-sensing sensor histidine kinase AgrC -
  ACK2VV_RS09915 (ACK2VV_09915) agrA 2013694..2014413 (+) 720 WP_409530657.1 quorum-sensing response regulator AgrA Regulator
  ACK2VV_RS09920 (ACK2VV_09920) - 2014485..2014594 (+) 110 Protein_1915 hypothetical protein -
  ACK2VV_RS09925 (ACK2VV_09925) - 2014782..2015741 (-) 960 WP_049311823.1 carbohydrate kinase family protein -
  ACK2VV_RS09930 (ACK2VV_09930) - 2015738..2017222 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  ACK2VV_RS09935 (ACK2VV_09935) - 2017371..2018321 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 28094.94 Da        Isoelectric Point: 5.8214

>NTDB_id=1082605 ACK2VV_RS09915 WP_409530657.1 2013694..2014413(+) (agrA) [Staphylococcus aureus strain GTVSS-008]
MYENFHCEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHD
PVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDI
MFFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 720 bp        

>NTDB_id=1082605 ACK2VV_RS09915 WP_409530657.1 2013694..2014413(+) (agrA) [Staphylococcus aureus strain GTVSS-008]
ATGTATGAAAATTTTCATTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGAT
AGAAGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACA
TAGGCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGAC
CCAGTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGA
TTTTATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAAT
TGTTGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATT
ATGTTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTT
AAAAGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTA
TAGATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-238)

Response regulator receiver domain (Response_reg)

(7-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.574

98.326

0.979

Multiple sequence alignment