Detailed information NTG1082603

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACK2VV_RS09185
• Genome accession: NZ_CP176712
• Coordinates: 1896271..1897314 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GTVSS-008
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1891271..1902314

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACK2VV_RS09155 (ACK2VV_09155)	-	1891692..1892948 (-)	1257	WP_001795108.1	aminopeptidase	-
ACK2VV_RS09160 (ACK2VV_09160)	-	1892951..1893151 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACK2VV_RS09165 (ACK2VV_09165)	-	1893298..1893762 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACK2VV_RS09170 (ACK2VV_09170)	-	1893769..1894044 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACK2VV_RS09175 (ACK2VV_09175)	-	1894322..1895539 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACK2VV_RS09180 (ACK2VV_09180)	vraR	1895652..1896281 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACK2VV_RS09185 (ACK2VV_09185)	vraS	1896271..1897314 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACK2VV_RS09190 (ACK2VV_09190)	liaF	1897311..1898012 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACK2VV_RS09195 (ACK2VV_09195)	-	1898027..1898413 (-)	387	WP_001110179.1	hypothetical protein	-
ACK2VV_RS09200 (ACK2VV_09200)	map	1898630..1899388 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACK2VV_RS09205 (ACK2VV_09205)	-	1899919..1900905 (+)	987	WP_000999717.1	FUSC family protein	-
ACK2VV_RS09210 (ACK2VV_09210)	-	1901336..1901749 (-)	414	WP_001557448.1	hypothetical protein	-
ACK2VV_RS09215 (ACK2VV_09215)	-	1901778..1901888 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1082603 ACK2VV_RS09185 WP_001017131.1 1896271..1897314(-) (vraS) [Staphylococcus aureus strain GTVSS-008]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1082603 ACK2VV_RS09185 WP_001017131.1 1896271..1897314(-) (vraS) [Staphylococcus aureus strain GTVSS-008]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1