Detailed information NTG1082389

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACK2VN_RS21600
• Genome accession: NZ_CP176690
• Coordinates: 4099565..4102165 (-)
• Length: 866 a.a.
• NCBI ID: WP_000365370.1
• Uniprot ID: A0A5M9GXY4
• Organism: Bacillus paranthracis strain GTVSS-022
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4094565..4107165

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACK2VN_RS21575 (ACK2VN_21575)	fabH	4095811..4096743 (-)	933	WP_001100543.1	beta-ketoacyl-ACP synthase III	-
ACK2VN_RS21580 (ACK2VN_21580)	comZ	4097322..4097498 (-)	177	WP_009879752.1	ComZ family protein	Regulator
ACK2VN_RS21585 (ACK2VN_21585)	-	4097552..4098424 (-)	873	WP_000486161.1	NAD-dependent epimerase/dehydratase family protein	-
ACK2VN_RS21590 (ACK2VN_21590)	-	4098454..4099188 (-)	735	WP_000028698.1	hydrolase	-
ACK2VN_RS21595 (ACK2VN_21595)	-	4099345..4099527 (+)	183	WP_001211114.1	YjzD family protein	-
ACK2VN_RS21600 (ACK2VN_21600)	clpC	4099565..4102165 (-)	2601	WP_000365370.1	ATP-dependent chaperone ClpB	Regulator
ACK2VN_RS21605 (ACK2VN_21605)	-	4102377..4102556 (-)	180	WP_000531421.1	YjzC family protein	-
ACK2VN_RS21610 (ACK2VN_21610)	-	4103051..4103860 (+)	810	WP_001041235.1	Cof-type HAD-IIB family hydrolase	-
ACK2VN_RS21615 (ACK2VN_21615)	-	4103966..4104106 (+)	141	WP_000516816.1	hypothetical protein	-
ACK2VN_RS21620 (ACK2VN_21620)	-	4104107..4104304 (+)	198	WP_000527391.1	DUF3813 domain-containing protein	-
ACK2VN_RS21625 (ACK2VN_21625)	-	4104330..4105187 (-)	858	WP_000364453.1	YitT family protein	-
ACK2VN_RS21630 (ACK2VN_21630)	-	4105288..4105419 (+)	132	WP_001120845.1	DUF3941 domain-containing protein	-
ACK2VN_RS21635 (ACK2VN_21635)	prsA	4105549..4106406 (+)	858	WP_001214227.1	peptidylprolyl isomerase PrsA	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97480.45 Da
• Isoelectric Point: 5.1561

>NTDB_id=1082389 ACK2VN_RS21600 WP_000365370.1 4099565..4102165(-) (clpC) [Bacillus paranthracis strain GTVSS-022]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGAEGLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDINQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEDDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=1082389 ACK2VN_RS21600 WP_000365370.1 4099565..4102165(-) (clpC) [Bacillus paranthracis strain GTVSS-022]
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCTCAATCTTTAGCGGTATCTCATCATCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGCTAGCAGTACGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCGTTAAAACAAGGTGCTGAAGGTTTAATTAAGAAAAAGCCCTCTGTAACGGGAAGCGGTGCAGAA
GCAGGTAAATTATATATAACAGGTGCTTTGCAACAACTGCTTGTAAGAGCAGGAAAAGAAGCAGAAAAATTGCAAGATGA
TTACATTTCAGTTGAACATGTATTACTTGCTTTTACTGAAGAAAAAGGCGATATAAACCAATTATTTACAAGATTTCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTAAGAGCGGGGAAAATTGACCCTGTTATCGGCCGCGA
TAGTGAAATTCGCCGCGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCAGTTTTAATTGGTGAACCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGGTTAGCACAGCGTATTGTGAAAAAGGATGTACCTGAAGGATTAAAAGATAGAACAATT
TTTGCATTAGATATGAGTGCGCTTGTAGCTGGAGCGAAATTCCGCGGTGAGTTTGAGGAGCGTCTCCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGTATTTTACTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGTAAAACAGAAG
GCGCAATGGATGCAGGAAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACGACGTTAGAT
GAATATCGTAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGCTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCAGTTTTATCAGATCGATATATTTCGGACCGTTTCTTACCAGATAAAGCAATTGATCTTGTCGATGAAGCG
TGTGCAACAATTCGTACAGAAATCGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTAGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAAAAGGACTTTGGTAGCCAAGAACGTCTAAAAACGTTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCCAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAGAGCAGCGGAACTTCGCCACGG
AAAAATTCCTGCAATTGAAAAAGAGTTAAAAGAAGCAGAAGAAATGGGCGCGCATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATTGCTGATATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGTGAGAAATTATTACGATTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGCTTAGTATC
AGACGCAGTTCTTCGTGCGCGCGCAGGTATCAAAGACCCGAACCGTCCGATTGGTTCCTTCATTTTCTTAGGACCTACTG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCATTATTCGATAGTGAAGAACAAATGATTCGTATTGATATG
TCTGAGTATATGGAGAAACACGCGGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCGTATTCGGTTATTTTATTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGACGGTCGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGATGATGGCTCCATTAAAGAGGAATCAAGAGA
GCTTGTAATGGGACAATTAAGAGGACATTTCCGACCAGAGTTTTTAAACCGTGTCGACGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCACATTACG
GTAGAATTAACAGACGCAGCGAAAGAGTTTGTTGTCGAAGCTGGCTTCGATCCGATGTACGGAGCCCGTCCATTAAAAAG
ATATGTACAGCGTCAAGTTGAGACGAAATTAGCGAGAGAATTAATTGCAGGAACGATTACTGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAGTAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• AAA lid domain (AAA_lid_9) (345-447)

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

3D structure

• AlphaFold DB: A0A5M9GXY4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	47.199	82.448	0.389