Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   FE90_RS04365 Genome accession   NZ_CP008695
Coordinates   841816..842292 (-) Length   158 a.a.
NCBI ID   WP_011017701.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M23ND     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 836816..847292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE90_RS04350 (FE90_0869) fbp54 837628..839280 (+) 1653 WP_038433466.1 Rqc2 family fibronectin-binding protein Fbp54 -
  FE90_RS04355 (FE90_0870) - 839340..840587 (-) 1248 WP_030126713.1 tetratricopeptide repeat protein -
  FE90_RS04360 (FE90_0871) - 840577..841758 (-) 1182 WP_038433467.1 AI-2E family transporter -
  FE90_RS04365 (FE90_0872) mutX 841816..842292 (-) 477 WP_011017701.1 NUDIX hydrolase Machinery gene
  FE90_RS10350 - 842700..842783 (-) 84 WP_420014349.1 hypothetical protein -
  FE90_RS04370 (FE90_0873) speh 842896..843605 (-) 710 Protein_854 streptococcal pyrogenic exotoxin SpeH -
  FE90_RS04375 (FE90_0875) spei 843631..844308 (-) 678 WP_080286815.1 streptococcal pyrogenic exotoxin SpeI -
  FE90_RS04380 (FE90_0876) - 844575..845327 (-) 753 WP_038433469.1 CHAP domain-containing protein -
  FE90_RS04385 (FE90_0877) - 845329..845661 (-) 333 WP_021733507.1 phage holin -
  FE90_RS04390 (FE90_0878) - 845674..845994 (-) 321 WP_021733504.1 hypothetical protein -
  FE90_RS04395 (FE90_0879) - 846005..846616 (-) 612 WP_038433470.1 DUF1366 domain-containing protein -
  FE90_RS09990 (FE90_0880) - 846619..846780 (-) 162 WP_002987333.1 hypothetical protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18474.74 Da        Isoelectric Point: 4.3268

>NTDB_id=108117 FE90_RS04365 WP_011017701.1 841816..842292(-) (mutX) [Streptococcus pyogenes strain M23ND]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVIEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=108117 FE90_RS04365 WP_011017701.1 841816..842292(-) (mutX) [Streptococcus pyogenes strain M23ND]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTATAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment