Detailed information NTG1080917

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACKZ7S_RS09985
• Genome accession: NZ_CP176565
• Coordinates: 2000273..2001316 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain V0353
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1995273..2006316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKZ7S_RS09955 (ACKZ7S_09955)	-	1995694..1996950 (-)	1257	WP_001793428.1	aminopeptidase	-
ACKZ7S_RS09960 (ACKZ7S_09960)	-	1996953..1997153 (-)	201	WP_000180462.1	DUF1128 family protein	-
ACKZ7S_RS09965 (ACKZ7S_09965)	-	1997300..1997764 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACKZ7S_RS09970 (ACKZ7S_09970)	-	1997771..1998046 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACKZ7S_RS09975 (ACKZ7S_09975)	-	1998324..1999541 (+)	1218	WP_072491831.1	YihY/virulence factor BrkB family protein	-
ACKZ7S_RS09980 (ACKZ7S_09980)	vraR	1999654..2000283 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ACKZ7S_RS09985 (ACKZ7S_09985)	vraS	2000273..2001316 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACKZ7S_RS09990 (ACKZ7S_09990)	liaF	2001313..2002014 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACKZ7S_RS09995 (ACKZ7S_09995)	-	2002029..2002415 (-)	387	WP_001110174.1	hypothetical protein	-
ACKZ7S_RS10000 (ACKZ7S_10000)	map	2002632..2003390 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACKZ7S_RS10005 (ACKZ7S_10005)	-	2003916..2004902 (+)	987	WP_000999713.1	FUSC family protein	-
ACKZ7S_RS10010 (ACKZ7S_10010)	-	2005091..2005504 (-)	414	WP_162635938.1	hypothetical protein	-
ACKZ7S_RS10015 (ACKZ7S_10015)	-	2005533..2005643 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1080917 ACKZ7S_RS09985 WP_001017131.1 2000273..2001316(-) (vraS) [Staphylococcus aureus strain V0353]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1080917 ACKZ7S_RS09985 WP_001017131.1 2000273..2001316(-) (vraS) [Staphylococcus aureus strain V0353]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1