Detailed information NTG1080878

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACKZ7T_RS10080
• Genome accession: NZ_CP176564
• Coordinates: 2026613..2027656 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain V0641
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2021613..2032656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKZ7T_RS10050 (ACKZ7T_10050)	-	2022034..2023290 (-)	1257	WP_250415481.1	aminopeptidase	-
ACKZ7T_RS10055 (ACKZ7T_10055)	-	2023293..2023493 (-)	201	WP_000180462.1	DUF1128 family protein	-
ACKZ7T_RS10060 (ACKZ7T_10060)	-	2023640..2024104 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACKZ7T_RS10065 (ACKZ7T_10065)	-	2024111..2024386 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACKZ7T_RS10070 (ACKZ7T_10070)	-	2024664..2025881 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACKZ7T_RS10075 (ACKZ7T_10075)	vraR	2025994..2026623 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ACKZ7T_RS10080 (ACKZ7T_10080)	vraS	2026613..2027656 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACKZ7T_RS10085 (ACKZ7T_10085)	liaF	2027653..2028354 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACKZ7T_RS10090 (ACKZ7T_10090)	-	2028369..2028755 (-)	387	WP_250415484.1	hypothetical protein	-
ACKZ7T_RS10095 (ACKZ7T_10095)	map	2028972..2029730 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACKZ7T_RS10100 (ACKZ7T_10100)	-	2030255..2031241 (+)	987	WP_409481362.1	FUSC family protein	-
ACKZ7T_RS10105 (ACKZ7T_10105)	-	2031430..2031843 (-)	414	WP_250414980.1	hypothetical protein	-
ACKZ7T_RS10110 (ACKZ7T_10110)	-	2031872..2031984 (-)	113	Protein_1952	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1080878 ACKZ7T_RS10080 WP_001017131.1 2026613..2027656(-) (vraS) [Staphylococcus aureus strain V0641]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1080878 ACKZ7T_RS10080 WP_001017131.1 2026613..2027656(-) (vraS) [Staphylococcus aureus strain V0641]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1