Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACK2WG_RS06230 Genome accession   NZ_CP176536
Coordinates   1220346..1221002 (+) Length   218 a.a.
NCBI ID   WP_014113374.1    Uniprot ID   G4NWF3
Organism   Bacillus spizizenii strain 29-4     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1215346..1226002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2WG_RS06200 (ACK2WG_06200) oppF 1215591..1216508 (+) 918 WP_114150709.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACK2WG_RS06205 (ACK2WG_06205) - 1216614..1217828 (+) 1215 WP_409509774.1 MFS transporter -
  ACK2WG_RS06210 (ACK2WG_06210) - 1218005..1218583 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACK2WG_RS06215 (ACK2WG_06215) spx 1218764..1219159 (+) 396 WP_003239281.1 transcriptional regulator Spx -
  ACK2WG_RS06220 (ACK2WG_06220) - 1219414..1220070 (-) 657 WP_003224601.1 TerC family protein -
  ACK2WG_RS06225 (ACK2WG_06225) - 1220254..1220379 (+) 126 WP_120698858.1 hypothetical protein -
  ACK2WG_RS06230 (ACK2WG_06230) mecA 1220346..1221002 (+) 657 WP_014113374.1 adaptor protein MecA Regulator
  ACK2WG_RS06235 (ACK2WG_06235) - 1220997..1221118 (-) 122 Protein_1175 hypothetical protein -
  ACK2WG_RS06240 (ACK2WG_06240) coiA 1221162..1222313 (+) 1152 WP_409509606.1 competence protein CoiA Machinery gene
  ACK2WG_RS06245 (ACK2WG_06245) pepF 1222543..1224372 (+) 1830 WP_166854689.1 oligoendopeptidase F -
  ACK2WG_RS06250 (ACK2WG_06250) - 1224410..1224577 (-) 168 WP_041520918.1 hypothetical protein -
  ACK2WG_RS06255 (ACK2WG_06255) spxH 1224891..1225790 (-) 900 WP_014113378.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25730.60 Da        Isoelectric Point: 4.1174

>NTDB_id=1080766 ACK2WG_RS06230 WP_014113374.1 1220346..1221002(+) (mecA) [Bacillus spizizenii strain 29-4]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFGNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1080766 ACK2WG_RS06230 WP_014113374.1 1220346..1221002(+) (mecA) [Bacillus spizizenii strain 29-4]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAGGAAGAGGAAT
TTGCTGTGGAAGGCCCTCTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATTGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGGTTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTGGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTGGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4NWF3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment