Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   ACKW6F_RS06675 Genome accession   NZ_CP176527
Coordinates   1341707..1343809 (-) Length   700 a.a.
NCBI ID   WP_149125704.1    Uniprot ID   -
Organism   Bacillus safensis strain D-62     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1336707..1348809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKW6F_RS06650 (ACKW6F_06650) - 1337124..1337366 (+) 243 WP_024424676.1 aspartyl-phosphate phosphatase Spo0E family protein -
  ACKW6F_RS06655 (ACKW6F_06655) - 1337413..1338918 (-) 1506 WP_044331882.1 ATP-binding protein -
  ACKW6F_RS06660 (ACKW6F_06660) - 1339123..1339578 (+) 456 WP_044331884.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACKW6F_RS06665 (ACKW6F_06665) motB 1339771..1340541 (-) 771 WP_024424679.1 flagellar motor protein MotB -
  ACKW6F_RS06670 (ACKW6F_06670) motA 1340534..1341328 (-) 795 WP_024424680.1 flagellar motor stator protein MotA -
  ACKW6F_RS06675 (ACKW6F_06675) clpC 1341707..1343809 (-) 2103 WP_149125704.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  ACKW6F_RS06680 (ACKW6F_06680) - 1344054..1345097 (+) 1044 WP_034623360.1 membrane protein -
  ACKW6F_RS06685 (ACKW6F_06685) queC 1345372..1346028 (+) 657 WP_024424683.1 7-cyano-7-deazaguanine synthase QueC -
  ACKW6F_RS06690 (ACKW6F_06690) queD 1346029..1346469 (+) 441 WP_149125703.1 6-carboxytetrahydropterin synthase QueD -
  ACKW6F_RS06695 (ACKW6F_06695) queE 1346462..1347193 (+) 732 WP_056766298.1 7-carboxy-7-deazaguanine synthase QueE -
  ACKW6F_RS06700 (ACKW6F_06700) queF 1347209..1347706 (+) 498 WP_024426839.1 preQ(1) synthase -
  ACKW6F_RS06705 (ACKW6F_06705) - 1348137..1348499 (-) 363 WP_149125702.1 winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 700 a.a.        Molecular weight: 77996.57 Da        Isoelectric Point: 4.9961

>NTDB_id=1080670 ACKW6F_RS06675 WP_149125704.1 1341707..1343809(-) (clpC) [Bacillus safensis strain D-62]
MRCQHCQVNEATIRLNMQVNSSRSQMVLCEDCYTSLMEQSKMKMGPQLFGGSSFFSQAAGHAPNMEQPKQKGLLDELGRN
LTDGANAGLIDPVIGRDEEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIASGDVPNKLKNKQIYLLDVSSLVA
NTGVRGQFEERMKQLIKELQSRKNIILFVDEIHLLVGAGSAEGSMDAGNILKPALARGELQLVGATTLKEYRQIEKDAAL
ERRFQPVIVDEPTQDEAIDILKGIQDKYEAYHGVTYSDEAIKACVQLSSRYIQDRHLPDKAIDLMDEAGSKANLSIDAAS
EDELTNRLTEIAAEKQAALKEEQYEKAAKLRDEEEAIEARLQNKTTEKEHIVTAEDIQAIVEQKTGIPVGKLQADEQTKM
KEIDVRLKARVIGQEHAVDKVAKAVKRSRAGLKSKHRPTGSFLFVGPTGVGKTELSKTLAEELFGSRDAIIRLDMSEYME
KHSVSKLIGSPPGYVGHDEAGQLTEKVRRKPYSIILLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGTADKTVKVGFQSDQEEAFEEQSLIDSLSSYFKPEFLNRFDSIIQFDSLDREDLVKIVDLLLNELSEQLKEQNLTVHVT
NEAKEKIAELGYHPAFGARPLRRTIQEHVEDQMTEILLEEEQLSGFTVDVEHDEIVVKKG

Nucleotide


Download         Length: 2103 bp        

>NTDB_id=1080670 ACKW6F_RS06675 WP_149125704.1 1341707..1343809(-) (clpC) [Bacillus safensis strain D-62]
ATGCGTTGTCAACATTGTCAAGTAAATGAAGCAACTATTCGCCTGAATATGCAAGTAAATTCGTCCCGGAGCCAAATGGT
TTTATGTGAAGACTGCTATACCTCTTTGATGGAGCAGTCAAAAATGAAAATGGGACCTCAGCTCTTTGGAGGAAGTTCAT
TCTTCTCTCAGGCAGCAGGTCATGCCCCAAACATGGAGCAGCCAAAGCAAAAAGGCTTACTCGATGAGCTCGGCCGTAAC
TTAACAGATGGAGCAAATGCTGGTTTAATTGATCCAGTCATTGGCCGTGATGAAGAAGTCGCAAGAGTCATTGAGATTTT
AAATAGAAGAAATAAAAATAACCCTGTTCTTATTGGTGAACCAGGTGTTGGGAAAACAGCGATCGCAGAAGGACTCGCGC
TCAAAATTGCGAGCGGCGATGTGCCAAATAAATTAAAGAACAAACAAATCTATTTATTAGATGTTTCTTCACTTGTCGCA
AACACAGGTGTACGCGGTCAATTTGAGGAAAGAATGAAGCAGTTAATCAAAGAACTGCAAAGCCGTAAAAATATCATCTT
ATTTGTAGATGAAATCCACCTTCTTGTGGGCGCAGGATCTGCAGAAGGATCAATGGATGCTGGAAACATTTTAAAACCAG
CCCTTGCAAGAGGTGAACTGCAGCTAGTAGGTGCGACGACATTAAAAGAATATCGCCAAATTGAAAAAGATGCTGCACTC
GAACGGCGCTTCCAGCCCGTCATCGTAGATGAGCCAACACAAGATGAAGCGATCGACATCTTAAAAGGCATTCAAGATAA
ATACGAGGCCTATCATGGTGTCACCTATTCAGATGAAGCAATCAAAGCGTGTGTTCAATTATCTTCGCGGTATATTCAAG
ACCGTCATTTACCGGATAAAGCCATTGATTTAATGGATGAAGCTGGTTCAAAAGCGAACCTCTCCATTGATGCAGCAAGT
GAAGATGAGCTGACAAATCGATTAACGGAAATTGCCGCAGAAAAACAAGCTGCGCTAAAAGAAGAACAATATGAAAAAGC
AGCGAAGCTTCGCGATGAAGAAGAAGCCATTGAAGCAAGACTTCAAAACAAAACAACTGAAAAAGAGCATATCGTTACAG
CAGAGGACATTCAGGCCATTGTGGAACAAAAAACAGGCATTCCTGTCGGGAAACTCCAAGCAGACGAACAAACCAAAATG
AAAGAAATTGACGTCCGTCTAAAAGCACGAGTGATTGGGCAGGAGCATGCGGTTGATAAAGTGGCCAAAGCCGTGAAAAG
AAGCAGAGCTGGATTAAAATCGAAACATAGACCAACAGGCTCCTTCCTTTTCGTTGGACCAACAGGTGTCGGGAAAACCG
AATTGTCTAAAACGTTAGCTGAAGAATTATTCGGTTCAAGAGATGCGATCATTCGTTTAGATATGAGTGAGTACATGGAA
AAACACTCTGTGTCCAAACTCATCGGTTCTCCTCCTGGTTACGTTGGACATGATGAAGCTGGCCAGCTGACTGAAAAAGT
GCGCAGAAAACCATACAGCATCATTTTGCTGGATGAAATCGAAAAAGCACACCCAGATGTACAGCACATGTTCCTGCAAA
TCATGGAAGACGGCCGCTTAACAGACAGCCAAGGCAGAACGGTCAGCTTTAAAGATACAGTCATCATCATGACAAGTAAC
GCAGGCACCGCAGATAAAACAGTCAAAGTGGGCTTCCAATCTGATCAGGAAGAAGCGTTTGAGGAACAATCACTCATTGA
TTCACTGAGCAGCTACTTCAAACCAGAATTTTTGAACCGTTTTGACAGCATCATTCAATTTGATTCACTAGACAGAGAGG
ATTTAGTGAAGATTGTTGATCTTCTGCTCAATGAGCTGTCAGAGCAATTAAAAGAGCAGAATTTAACAGTTCATGTCACA
AATGAAGCAAAAGAAAAGATTGCAGAGCTTGGATATCATCCTGCATTTGGTGCTCGTCCACTTCGAAGAACCATCCAAGA
GCACGTTGAAGACCAAATGACGGAGATCCTGCTTGAAGAGGAGCAGCTTTCTGGATTTACTGTGGATGTTGAACATGACG
AAATCGTCGTAAAAAAAGGATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(437-604)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-687)

AAA lid domain (AAA_lid_9)

(253-353)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

57.046

100

0.601
  clpE Streptococcus mutans UA159

56.469

100

0.599
  clpE Streptococcus pneumoniae Rx1

55.663

100

0.576
  clpE Streptococcus pneumoniae D39

55.663

100

0.576
  clpE Streptococcus pneumoniae R6

55.663

100

0.576
  clpE Streptococcus pneumoniae TIGR4

55.663

100

0.576
  clpC Bacillus subtilis subsp. subtilis str. 168

53.881

95.714

0.516
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.086

93.143

0.439
  clpC Streptococcus thermophilus LMD-9

46.368

92.429

0.429
  clpC Streptococcus thermophilus LMG 18311

46.213

92.429

0.427
  clpC Streptococcus mutans UA159

44.172

93.143

0.411
  clpC Streptococcus pneumoniae TIGR4

44.904

89.714

0.403
  clpC Streptococcus pneumoniae Rx1

45.104

89

0.401
  clpC Streptococcus pneumoniae D39

45.104

89

0.401

Multiple sequence alignment