Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACKWCM_RS05780 Genome accession   NZ_CP176416
Coordinates   1190966..1191631 (+) Length   221 a.a.
NCBI ID   WP_024425038.1    Uniprot ID   A0AAX0Z5Z8
Organism   Bacillus safensis strain GUCCb3-7     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1185966..1196631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWCM_RS05750 (ACKWCM_05750) - 1186299..1187378 (+) 1080 WP_024425042.1 ABC transporter ATP-binding protein -
  ACKWCM_RS05755 (ACKWCM_05755) - 1187380..1188300 (+) 921 WP_024425041.1 ABC transporter ATP-binding protein -
  ACKWCM_RS05760 (ACKWCM_05760) - 1188405..1188692 (+) 288 WP_149125764.1 hypothetical protein -
  ACKWCM_RS05765 (ACKWCM_05765) - 1188830..1189408 (+) 579 WP_024425040.1 GNAT family N-acetyltransferase -
  ACKWCM_RS05770 (ACKWCM_05770) spxA 1189602..1189997 (+) 396 WP_003211421.1 transcriptional regulator SpxA -
  ACKWCM_RS05775 (ACKWCM_05775) - 1190037..1190702 (-) 666 WP_149125763.1 TerC family protein -
  ACKWCM_RS05780 (ACKWCM_05780) mecA 1190966..1191631 (+) 666 WP_024425038.1 adaptor protein MecA Regulator
  ACKWCM_RS05785 (ACKWCM_05785) cls 1191719..1193239 (+) 1521 WP_044334757.1 cardiolipin synthase -
  ACKWCM_RS05790 (ACKWCM_05790) - 1193402..1194562 (+) 1161 WP_149125762.1 competence protein CoiA -
  ACKWCM_RS05795 (ACKWCM_05795) pepF 1194777..1196603 (+) 1827 WP_311165140.1 oligoendopeptidase F -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 26414.19 Da        Isoelectric Point: 4.0153

>NTDB_id=1079959 ACKWCM_RS05780 WP_024425038.1 1190966..1191631(+) (mecA) [Bacillus safensis strain GUCCb3-7]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIVVTKAQL
SKDGQKLELPIPEDKKDQTDEESLDALLDDFHKEEQDQEDHNEKDKKLQLQFVLKMDDFEDLIALSQLNMQDFTTSLYSF
ENRYYLYVDFHEDLSDEQVENKLSILLEYAHESVVSIYRLKEYGQLIIEGNALETIQQHFS

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1079959 ACKWCM_RS05780 WP_024425038.1 1190966..1191631(+) (mecA) [Bacillus safensis strain GUCCb3-7]
ATGGAAATCGAAAGAATAAATGAACATACAGTAAAATTTTATATTTCCTACGGTGATATTGAAGATCGCGGATTTGACCG
TGAAGAGATTTGGTATAATCGTGAGCGCAGTGAAGAGCTGTTTTGGGAAGTAATGGACGAAGTGCACGAAGAAGAAGAAT
TTGCAGTAGAGGGGCCGCTTTGGATTCAAGTACAGGCACTTGATAAAGGTCTTGAAATTGTCGTGACAAAAGCCCAACTT
TCTAAAGATGGACAAAAGCTCGAATTGCCGATTCCAGAAGATAAAAAAGATCAAACAGATGAAGAAAGCTTAGACGCACT
GCTTGATGATTTTCATAAAGAAGAGCAAGATCAAGAAGACCATAATGAGAAGGACAAAAAACTTCAACTTCAATTCGTGT
TGAAAATGGATGACTTTGAAGATTTGATTGCACTTTCTCAATTAAATATGCAGGATTTTACCACAAGTTTATATTCGTTT
GAAAACCGTTATTATCTATATGTTGACTTCCACGAGGATTTGTCAGATGAGCAAGTGGAAAATAAGCTCAGCATTTTGCT
TGAATATGCTCATGAATCAGTGGTCAGCATCTACAGACTGAAAGAATACGGTCAGCTGATTATCGAAGGGAATGCCCTTG
AAACGATTCAACAGCACTTCTCGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

76.923

100

0.769

Multiple sequence alignment