Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ACKVMU_RS12770 Genome accession   NZ_CP176094
Coordinates   2637719..2639530 (-) Length   603 a.a.
NCBI ID   WP_010734244.1    Uniprot ID   A0A2M9FSJ9
Organism   Enterococcus mundtii strain Dm     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2632719..2644530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKVMU_RS12760 (ACKVMU_12760) abc-f 2634253..2635725 (-) 1473 WP_010734246.1 ribosomal protection-like ABC-F family protein -
  ACKVMU_RS12765 (ACKVMU_12765) - 2636082..2637113 (-) 1032 WP_023520418.1 zinc-binding dehydrogenase -
  ACKVMU_RS12770 (ACKVMU_12770) pepF 2637719..2639530 (-) 1812 WP_010734244.1 oligoendopeptidase F Regulator
  ACKVMU_RS12775 (ACKVMU_12775) - 2639661..2640656 (-) 996 WP_153830535.1 competence protein CoiA -
  ACKVMU_RS12780 (ACKVMU_12780) - 2640777..2641427 (-) 651 WP_010734242.1 adaptor protein MecA -
  ACKVMU_RS12785 (ACKVMU_12785) spxA 2641591..2641989 (-) 399 WP_019723016.1 transcriptional regulator SpxA -
  ACKVMU_RS12790 (ACKVMU_12790) - 2642743..2643465 (+) 723 WP_010734240.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 69036.32 Da        Isoelectric Point: 4.7420

>NTDB_id=1079686 ACKVMU_RS12770 WP_010734244.1 2637719..2639530(-) (pepF) [Enterococcus mundtii strain Dm]
MSETTKLPNREDLPEKLTWDLTPIFSSDQEFDKKYEELTEELKNSEHYKGTLGNGATAFLEALEFVLTMYRKVELIYVYS
HLKNDQDTTNTTYQALYARAGSLLSKVSEAIAWYEPEVLQLSDEQIWQYFEEEPKLEVYRHYVKQMVDNRAHILSADQEA
LLAGAGEIFGASSGTFAVLNNADLEFPTITGENGEKIQLSHGVYGQLLESTNREVREAAFKGLYSVYAQFRNTFASTLGT
HIKGHNFKAKARRYASAREAALSNNHIPESVYDTLVTVVNKHLPLLHRYMELRKRLLNVDTLHMYDLYTPVLGEAPIKFT
YEEAVEKAIESLAPMGEEYLAVVKEAFSNRWIDVVENKGKRSGAYSSGSYDTNPYILMNWHDTLDQLFTLVHEMGHSVHS
YFTRSNQPFVYGDYSIFLAEIASTTNENILTEHLLATEEDPRVRAYVLNHYLDGFKGTIFRQTQFAEFEHFMHQEDAKGT
PLTSEYLSESYGELNAKYYGPAVEKDPEIKDEWARIPHFYYNYYVYQYSTGFSAASALAKKIWEKEPGALDAYLTYLKAG
NSDYPVEVMKKAGVDMTQAAYIEDAMAVFEQRLNELEALVEEL

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=1079686 ACKVMU_RS12770 WP_010734244.1 2637719..2639530(-) (pepF) [Enterococcus mundtii strain Dm]
ATGAGCGAAACAACGAAGTTACCAAATAGAGAAGATTTGCCTGAAAAATTGACATGGGACCTAACACCAATCTTTTCAAG
CGATCAAGAATTTGATAAAAAGTACGAAGAATTGACTGAAGAATTAAAAAATTCTGAGCATTATAAAGGAACATTAGGTA
ATGGAGCAACAGCATTTTTGGAGGCGCTTGAATTTGTCTTAACAATGTATCGTAAAGTTGAGCTTATTTATGTCTATTCC
CATTTAAAAAATGACCAAGATACGACAAATACGACATATCAAGCATTGTATGCTCGTGCTGGAAGTTTACTTTCAAAAGT
GAGTGAAGCAATTGCTTGGTATGAGCCAGAAGTATTGCAACTTTCTGATGAGCAAATTTGGCAATATTTTGAAGAAGAAC
CAAAATTAGAAGTTTATCGTCATTATGTCAAACAAATGGTTGATAACCGCGCACACATCTTGTCAGCAGATCAGGAAGCA
TTACTTGCTGGAGCCGGAGAAATCTTTGGTGCTTCAAGTGGTACATTTGCAGTATTGAATAATGCTGATTTAGAGTTCCC
AACAATCACTGGCGAGAATGGTGAAAAGATCCAATTATCGCATGGTGTATATGGTCAATTATTAGAAAGTACCAATCGTG
AAGTACGTGAAGCGGCGTTCAAAGGACTATACAGCGTATATGCACAATTTAGAAACACTTTTGCTTCCACACTTGGGACG
CATATCAAAGGGCACAACTTCAAAGCCAAAGCACGTCGATACGCTTCTGCCAGAGAAGCTGCACTAAGCAATAACCATAT
TCCTGAAAGTGTGTATGATACTTTAGTTACTGTTGTGAACAAACATTTGCCGTTATTGCATCGATATATGGAACTACGGA
AACGACTATTAAACGTAGATACATTGCATATGTATGATCTGTATACGCCAGTATTAGGTGAAGCACCAATCAAATTTACG
TATGAAGAAGCAGTAGAAAAAGCCATTGAATCACTTGCGCCAATGGGAGAAGAATATCTGGCTGTCGTAAAAGAAGCATT
TTCAAACCGTTGGATCGATGTAGTCGAGAATAAAGGGAAACGCAGTGGCGCTTATTCTTCTGGTAGTTATGATACCAACC
CTTACATTCTGATGAACTGGCATGATACGTTGGATCAACTGTTCACCTTGGTCCATGAAATGGGACATAGTGTCCACAGC
TATTTCACACGTTCGAACCAACCTTTCGTCTATGGTGATTATTCAATCTTTTTAGCCGAGATCGCGTCAACAACAAATGA
AAATATTTTGACCGAACATTTATTAGCGACCGAAGAAGATCCTCGGGTTCGTGCCTATGTCTTGAATCATTATTTAGATG
GTTTTAAAGGAACAATTTTCCGTCAAACACAATTTGCAGAGTTTGAACACTTCATGCATCAAGAAGATGCAAAAGGAACA
CCTTTGACGAGTGAGTACCTAAGTGAAAGCTATGGCGAATTAAATGCTAAGTATTATGGTCCAGCTGTTGAAAAAGATCC
AGAAATCAAAGATGAATGGGCGCGTATCCCACATTTCTACTATAATTATTATGTCTATCAATACTCAACAGGATTTTCTG
CTGCATCTGCTTTAGCGAAGAAAATCTGGGAGAAAGAACCAGGCGCATTAGATGCTTACCTAACGTATCTAAAAGCAGGA
AACAGCGATTATCCAGTAGAAGTAATGAAGAAAGCTGGTGTGGACATGACCCAAGCAGCTTATATTGAAGATGCAATGGC
CGTGTTTGAACAACGATTAAATGAATTAGAAGCATTAGTGGAAGAATTATAG

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2M9FSJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

55.556

98.507

0.547

Multiple sequence alignment