Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACJGE4_RS06015 Genome accession   NZ_CP174519
Coordinates   1167652..1168308 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain JD-3     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1162652..1173308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJGE4_RS05985 (ACJGE4_05985) oppF 1163181..1164098 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACJGE4_RS05990 (ACJGE4_05990) - 1164205..1165392 (+) 1188 WP_015239569.1 putative glycoside hydrolase -
  ACJGE4_RS05995 (ACJGE4_05995) - 1165510..1166088 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ACJGE4_RS06000 (ACJGE4_06000) spx 1166267..1166662 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  ACJGE4_RS06005 (ACJGE4_06005) - 1166720..1167376 (-) 657 WP_015239570.1 TerC family protein -
  ACJGE4_RS06010 (ACJGE4_06010) - 1167559..1167669 (+) 111 Protein_1122 adaptor protein MecA -
  ACJGE4_RS06015 (ACJGE4_06015) mecA 1167652..1168308 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACJGE4_RS06020 (ACJGE4_06020) - 1168459..1169619 (+) 1161 WP_069006905.1 competence protein CoiA family protein -
  ACJGE4_RS06025 (ACJGE4_06025) pepF 1169847..1171676 (+) 1830 WP_094031915.1 oligoendopeptidase F Regulator
  ACJGE4_RS06030 (ACJGE4_06030) - 1171714..1171881 (-) 168 WP_003155026.1 hypothetical protein -
  ACJGE4_RS06035 (ACJGE4_06035) spxH 1172167..1173069 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1077709 ACJGE4_RS06015 WP_003155032.1 1167652..1168308(+) (mecA) [Bacillus velezensis strain JD-3]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1077709 ACJGE4_RS06015 WP_003155032.1 1167652..1168308(+) (mecA) [Bacillus velezensis strain JD-3]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGATGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment