Detailed information NTG1076489

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: ACJEH8_RS13625
• Genome accession: NZ_CP174244
• Coordinates: 3060326..3061393 (-)
• Length: 355 a.a.
• NCBI ID: WP_011216540.1
• Uniprot ID: Q5WTC8
• Organism: Legionella pneumophila strain SPF580
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3055326..3066393

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEH8_RS13600 (ACJEH8_13600)	-	3055619..3056335 (-)	717	WP_408072749.1	dienelactone hydrolase family protein	-
ACJEH8_RS13605 (ACJEH8_13605)	-	3056618..3057484 (+)	867	WP_011216536.1	alpha/beta hydrolase	-
ACJEH8_RS13610 (ACJEH8_13610)	rpoH	3057616..3058470 (-)	855	WP_027266273.1	RNA polymerase sigma factor RpoH	-
ACJEH8_RS13615 (ACJEH8_13615)	ftsX	3058766..3059695 (-)	930	WP_011216538.1	permease-like cell division protein FtsX	-
ACJEH8_RS13620 (ACJEH8_13620)	ftsE	3059689..3060339 (-)	651	WP_011216539.1	cell division ATP-binding protein FtsE	-
ACJEH8_RS13625 (ACJEH8_13625)	pilA	3060326..3061393 (-)	1068	WP_011216540.1	signal recognition particle-docking protein FtsY	Machinery gene
ACJEH8_RS13630 (ACJEH8_13630)	-	3061456..3062781 (+)	1326	WP_011216541.1	pitrilysin family protein	-
ACJEH8_RS13635 (ACJEH8_13635)	-	3062778..3064082 (+)	1305	WP_011216542.1	pitrilysin family protein	-
ACJEH8_RS13640 (ACJEH8_13640)	rsmD	3064079..3064624 (+)	546	WP_011216543.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACJEH8_RS13645 (ACJEH8_13645)	dotD	3064699..3065190 (+)	492	WP_011216544.1	type IVB secretion system lipoprotein DotD	-
ACJEH8_RS13650 (ACJEH8_13650)	dotC	3065171..3066082 (+)	912	WP_011216545.1	type IVB secretion system protein DotC	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39056.55 Da
• Isoelectric Point: 6.1218

>NTDB_id=1076489 ACJEH8_RS13625 WP_011216540.1 3060326..3061393(-) (pilA) [Legionella pneumophila strain SPF580]
MIKWFKRNQNSEPNLDTEEQQDHAESSRESRLEEPRELTAKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGDAVYQTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Nucleotide

• Length: 1068 bp

>NTDB_id=1076489 ACJEH8_RS13625 WP_011216540.1 3060326..3061393(-) (pilA) [Legionella pneumophila strain SPF580]
ATGATTAAATGGTTTAAACGAAATCAAAATTCCGAACCAAATTTGGATACCGAAGAGCAGCAAGATCATGCCGAAAGCAG
CAGGGAATCCAGGCTTGAAGAGCCCCGGGAACTGACTGCCAAAGAGCCTTCGCCCAAAGAAAGTATTTTTGCCCGGTTTA
GGAAAGGCCTTAGCAAAACCCGTCATCAATTGGGGGAAGGCATAAGTCGGCTGCTGTTAGGTAAAAAAGAAATCAGCCAG
GAGTTACTCGAAGAGCTGGAGACCTTATTAATTAGTGCTGATTTAGGTTTGGACACCACTCAAGACGTATTGAAACAGCT
AAATGAAGGCTTGGCAAGAAAGCAACTGTCTAATGGTGACGCAGTTTATCAGACTTTAAAGACAAATTTGCAAACGATTT
TGAGCCAGGAAGAGAAACCGCTTTCCATAGAAACTGAAGACGGCTCTCCCTTTGTCATATTAATGGTTGGTGTCAATGGA
GCCGGTAAAACAACCACGATTGGTAAACTAGCCAAACAATTTCAAAAGCAGGGAAAAAAAGTTATGTTAGCTGCGGGGGA
TACGTTTCGGGCGGCTGCGGTGGAACAATTGCATGTATGGGGCGAAAGAAATGGCATACCTGTTATTGCCCAGCATACCG
GCGCTGACAGTGCCTCAGTAATTTTTGATGCTCTTCAGGCTGCCAAAGCGAGAAAAATAGATGTTTTAATCGCTGATACA
GCCGGGCGTTTGCATACTCAAAGCAATTTAATGGAAGAGTTGAAAAAAGTGAAAAGAGTCATGCAGAAACTCGATCCCAA
GGCACCTCATGAAACCATGTTGGTATTGGATGCGAGTATTGGGCAGAACGCCTTGGCTCAGGCAAAGCAGTTTCATGAAG
CAGTACAATTAACTGGAATTACTATGACCAAGCTTGATGGGACAGCCAAAGGCGGGATATTATTTGCTATAGCGAATGAT
TTGGGGATACCTTTTCGTTATTTAGGGGTAGGGGAGGGCATTGAAGATTTGAGGCCCTTTGACGCAGCGCAATTTGTTAG
TGCGATATTCGATGATGATCACATTTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (150-350)

• SRP54-type protein, helical bundle domain (SRP54_N) (64-130)

3D structure

• AlphaFold DB: Q5WTC8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	52.353	95.775	0.501