Detailed information NTG1076279

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: ACJEH6_RS13635
• Genome accession: NZ_CP174239
• Coordinates: 3060659..3061726 (-)
• Length: 355 a.a.
• NCBI ID: WP_011216540.1
• Uniprot ID: Q5WTC8
• Organism: Legionella pneumophila strain SPF586
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3055659..3066726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEH6_RS13610 (ACJEH6_13610)	-	3055952..3056668 (-)	717	WP_408072749.1	dienelactone hydrolase family protein	-
ACJEH6_RS13615 (ACJEH6_13615)	-	3056951..3057817 (+)	867	WP_011216536.1	alpha/beta hydrolase	-
ACJEH6_RS13620 (ACJEH6_13620)	rpoH	3057949..3058803 (-)	855	WP_027266273.1	RNA polymerase sigma factor RpoH	-
ACJEH6_RS13625 (ACJEH6_13625)	ftsX	3059099..3060028 (-)	930	WP_011216538.1	permease-like cell division protein FtsX	-
ACJEH6_RS13630 (ACJEH6_13630)	ftsE	3060022..3060672 (-)	651	WP_011216539.1	cell division ATP-binding protein FtsE	-
ACJEH6_RS13635 (ACJEH6_13635)	pilA	3060659..3061726 (-)	1068	WP_011216540.1	signal recognition particle-docking protein FtsY	Machinery gene
ACJEH6_RS13640 (ACJEH6_13640)	-	3061789..3063114 (+)	1326	WP_011216541.1	pitrilysin family protein	-
ACJEH6_RS13645 (ACJEH6_13645)	-	3063111..3064415 (+)	1305	WP_011216542.1	pitrilysin family protein	-
ACJEH6_RS13650 (ACJEH6_13650)	rsmD	3064412..3064957 (+)	546	WP_011216543.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACJEH6_RS13655 (ACJEH6_13655)	dotD	3065032..3065523 (+)	492	WP_011216544.1	type IVB secretion system lipoprotein DotD	-
ACJEH6_RS13660 (ACJEH6_13660)	dotC	3065504..3066415 (+)	912	WP_011216545.1	type IVB secretion system protein DotC	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39056.55 Da
• Isoelectric Point: 6.1218

>NTDB_id=1076279 ACJEH6_RS13635 WP_011216540.1 3060659..3061726(-) (pilA) [Legionella pneumophila strain SPF586]
MIKWFKRNQNSEPNLDTEEQQDHAESSRESRLEEPRELTAKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGDAVYQTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Nucleotide

• Length: 1068 bp

>NTDB_id=1076279 ACJEH6_RS13635 WP_011216540.1 3060659..3061726(-) (pilA) [Legionella pneumophila strain SPF586]
ATGATTAAATGGTTTAAACGAAATCAAAATTCCGAACCAAATTTGGATACCGAAGAGCAGCAAGATCATGCCGAAAGCAG
CAGGGAATCCAGGCTTGAAGAGCCCCGGGAACTGACTGCCAAAGAGCCTTCGCCCAAAGAAAGTATTTTTGCCCGGTTTA
GGAAAGGCCTTAGCAAAACCCGTCATCAATTGGGGGAAGGCATAAGTCGGCTGCTGTTAGGTAAAAAAGAAATCAGCCAG
GAGTTACTCGAAGAGCTGGAGACCTTATTAATTAGTGCTGATTTAGGTTTGGACACCACTCAAGACGTATTGAAACAGCT
AAATGAAGGCTTGGCAAGAAAGCAACTGTCTAATGGTGACGCAGTTTATCAGACTTTAAAGACAAATTTGCAAACGATTT
TGAGCCAGGAAGAGAAACCGCTTTCCATAGAAACTGAAGACGGCTCTCCCTTTGTCATATTAATGGTTGGTGTCAATGGA
GCCGGTAAAACAACCACGATTGGTAAACTAGCCAAACAATTTCAAAAGCAGGGAAAAAAAGTTATGTTAGCTGCGGGGGA
TACGTTTCGGGCGGCTGCGGTGGAACAATTGCATGTATGGGGCGAAAGAAATGGCATACCTGTTATTGCCCAGCATACCG
GCGCTGACAGTGCCTCAGTAATTTTTGATGCTCTTCAGGCTGCCAAAGCGAGAAAAATAGATGTTTTAATCGCTGATACA
GCCGGGCGTTTGCATACTCAAAGCAATTTAATGGAAGAGTTGAAAAAAGTGAAAAGAGTCATGCAGAAACTCGATCCCAA
GGCACCTCATGAAACCATGTTGGTATTGGATGCGAGTATTGGGCAGAACGCCTTGGCTCAGGCAAAGCAGTTTCATGAAG
CAGTACAATTAACTGGAATTACTATGACCAAGCTTGATGGGACAGCCAAAGGCGGGATATTATTTGCTATAGCGAATGAT
TTGGGGATACCTTTTCGTTATTTAGGGGTAGGGGAGGGCATTGAAGATTTGAGGCCCTTTGACGCAGCGCAATTTGTTAG
TGCGATATTCGATGATGATCACATTTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (150-350)

• SRP54-type protein, helical bundle domain (SRP54_N) (64-130)

3D structure

• AlphaFold DB: Q5WTC8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	52.353	95.775	0.501