Detailed information NTG1076276

Bioinformatically predicted

Overview

• Name: lqsT
• Type: Regulator
• Locus tag: ACJEH6_RS12435
• Genome accession: NZ_CP174239
• Coordinates: 2786674..2787936 (+)
• Length: 420 a.a.
• NCBI ID: WP_011216388.1
• Uniprot ID: Q5WTU5
• Organism: Legionella pneumophila strain SPF586
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2781674..2792936

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEH6_RS12425 (ACJEH6_12425)	ceg32	2782562..2785390 (+)	2829	WP_011216386.1	Dot/Icm T4SS effector Ceg32/SidI	-
ACJEH6_RS12430 (ACJEH6_12430)	mesI	2785392..2786279 (+)	888	WP_080020749.1	Dot/Icm T4SS effector metaeffector MesI	-
ACJEH6_RS12435 (ACJEH6_12435)	lqsT	2786674..2787936 (+)	1263	WP_011216388.1	HAMP domain-containing sensor histidine kinase	Regulator
ACJEH6_RS12440 (ACJEH6_12440)	-	2787984..2788679 (-)	696	WP_011216389.1	iron-containing redox enzyme family protein	-
ACJEH6_RS12445 (ACJEH6_12445)	sdjA	2789076..2791499 (-)	2424	WP_011216390.1	Dot/Icm T4SS effector SdjA	-
ACJEH6_RS12450 (ACJEH6_12450)	dupB	2791570..2792763 (-)	1194	WP_080020750.1	Dot/Icm T4SS effector deubiquitinase DupB/LaiF	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 48598.99 Da
• Isoelectric Point: 7.9744

>NTDB_id=1076276 ACJEH6_RS12435 WP_011216388.1 2786674..2787936(+) (lqsT) [Legionella pneumophila strain SPF586]
MQRLKNIFTAIYQYLLKETEDASHQITLFGIVMMINYPLFGVFWKLEHFQLTEEFILRITAALLCACLAFNQFWPRQLLK
FLPVFWYIVLLFCLPYFFAYLTLINNGSTLWLMNCVSAIFFLLLVSSVLGALVLLVSGVGLAFFHFYILSNNQFVYIPGT
ISLFSLIVTFIAAIIIGALFARDREITYAGRLSGMRMLAGSIAHDLRTPLASIYLQAELQELIVERLNNPEVQKDLKENL
SKITRGIEMSNQLIRMQLNNIQRDKLDTSTFAIYSIKKLLKASLEEYPFKENQKSLIHLNDKNDFSIWIDEVGFKNMMWN
LLKNSLEYIEETHKGEISIWLEQGWEKENFNYLHIKDTAKGLNHKEYEKIFDFFYSGRKDGTGLGLAYCKLLMQAAGGDI
SCKGKKNEFAHFTLKFPKID

Nucleotide

• Length: 1263 bp

>NTDB_id=1076276 ACJEH6_RS12435 WP_011216388.1 2786674..2787936(+) (lqsT) [Legionella pneumophila strain SPF586]
ATGCAAAGGTTAAAAAATATATTTACTGCAATTTACCAATATTTATTAAAAGAAACTGAAGATGCAAGCCACCAAATCAC
TTTATTTGGCATCGTCATGATGATTAATTACCCTCTTTTCGGAGTTTTCTGGAAACTGGAGCATTTTCAACTGACAGAAG
AATTTATTTTACGCATCACTGCAGCCCTCCTCTGTGCCTGTTTGGCATTTAATCAATTTTGGCCAAGACAATTATTAAAA
TTTCTACCTGTTTTTTGGTATATAGTTCTTCTCTTTTGTTTACCTTACTTTTTTGCTTATTTGACTCTCATAAACAATGG
CTCAACTCTTTGGCTAATGAATTGCGTATCCGCTATCTTTTTTCTTTTATTAGTCTCCAGTGTGTTGGGAGCTCTTGTAT
TGCTTGTATCAGGTGTTGGACTTGCTTTTTTTCATTTTTATATTTTATCAAATAATCAGTTTGTCTATATCCCAGGAACC
ATATCACTTTTTAGTTTAATTGTTACGTTTATTGCAGCAATAATCATTGGTGCTTTGTTTGCACGAGATAGAGAAATTAC
CTATGCCGGACGTTTATCGGGTATGCGCATGCTGGCTGGAAGTATCGCTCATGATTTAAGAACGCCGCTTGCCAGTATTT
ATTTACAAGCGGAATTACAGGAATTGATTGTCGAAAGATTAAATAATCCAGAAGTTCAAAAGGACCTGAAGGAAAATTTA
AGCAAAATTACTCGCGGTATAGAAATGAGTAATCAATTAATTCGTATGCAATTAAATAATATTCAACGAGACAAATTAGA
TACCAGTACATTTGCGATTTATTCCATCAAAAAATTACTCAAGGCGTCTTTAGAAGAATACCCTTTCAAAGAAAATCAAA
AATCATTGATTCATTTAAATGATAAAAATGATTTTTCCATATGGATTGATGAAGTGGGTTTTAAAAATATGATGTGGAAT
TTGCTAAAAAATAGTCTGGAATATATTGAGGAAACCCATAAAGGCGAAATCTCTATCTGGCTAGAACAAGGATGGGAGAA
AGAGAATTTTAATTACCTCCATATAAAAGATACAGCTAAAGGTTTAAATCATAAAGAATATGAAAAAATATTTGATTTCT
TCTATTCTGGCAGAAAAGATGGAACTGGTTTAGGCTTGGCCTATTGCAAACTTCTGATGCAAGCAGCAGGTGGTGATATT
TCGTGTAAAGGGAAAAAAAATGAATTCGCTCATTTCACTTTAAAATTCCCCAAAATTGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (310-417)

• His Kinase A (phospho-acceptor) domain (HisKA) (198-255)

3D structure

• AlphaFold DB: Q5WTU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lqsT	Legionella pneumophila subsp. pneumophila str. Philadelphia 1	99.048	100	0.99