Detailed information NTG1075468

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: ACJEHX_RS09390
• Genome accession: NZ_CP174220
• Coordinates: 2101525..2104257 (+)
• Length: 910 a.a.
• NCBI ID: WP_010947629.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain SPF647
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2096525..2109257

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEHX_RS09370 (ACJEHX_09370)	gstA	2096668..2097273 (-)	606	WP_015444385.1	glutathione transferase GstA	-
ACJEHX_RS09375 (ACJEHX_09375)	-	2097469..2098464 (-)	996	WP_015444384.1	hypothetical protein	-
ACJEHX_RS09380 (ACJEHX_09380)	-	2098505..2099767 (-)	1263	WP_010947627.1	serine hydrolase	-
ACJEHX_RS09385 (ACJEHX_09385)	gltX	2100014..2101426 (-)	1413	WP_015444383.1	glutamate--tRNA ligase	-
ACJEHX_RS09390 (ACJEHX_09390)	letS	2101525..2104257 (+)	2733	WP_010947629.1	two-component system sensor histidine kinase LetS	Regulator
ACJEHX_RS09395 (ACJEHX_09395)	-	2104354..2105598 (+)	1245	WP_010947630.1	6-phosphofructokinase	-
ACJEHX_RS09400 (ACJEHX_09400)	pilA2	2105595..2106008 (-)	414	WP_015444381.1	pilin	Machinery gene
ACJEHX_RS09405 (ACJEHX_09405)	pilA2	2106205..2106615 (-)	411	WP_016356941.1	pilin	Machinery gene
ACJEHX_RS09410 (ACJEHX_09410)	-	2106918..2107235 (+)	318	WP_010947633.1	BolA family transcriptional regulator	-
ACJEHX_RS09415 (ACJEHX_09415)	-	2107310..2108731 (+)	1422	WP_010947634.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103050.55 Da
• Isoelectric Point: 7.6619

>NTDB_id=1075468 ACJEHX_RS09390 WP_010947629.1 2101525..2104257(+) (letS) [Legionella pneumophila strain SPF647]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKELSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAIGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPEILIAEDNPVNKMLLTSLLNNNANITTVDDGEMAVTACEDKKFD
MILLDLHMPKLNGLEAAKMIRQKSLMNKHSPIVLITASSSDLSSIDMKKYGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIGLMHQKNVKGLADLAHKLHGACCFCGVPILQKRVAQLERLARRT
ANADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=1075468 ACJEHX_RS09390 WP_010947629.1 2101525..2104257(+) (letS) [Legionella pneumophila strain SPF647]
ATGTTGAAAAGTATTGGTATTAAATATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
TTTTTTTTATAACGGCCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTATATTAGGCAATTAC
TTCCAGCAGCCCAGTATGCCATGCTTCGCAATGATTACCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCT
GAGGTAAAAGCTTTGGCATTTTATAATGCTGATGGTCGATTAATCGCTTATCGTGGTGGCAAGCACTCTATTCATAAACC
ATTCAATCCACCTGACTATACAGGTGACTACATTGAAAGTAAGCAAATTAATCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGCACAGAATTCAAAGAGCTTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCCATTGACATTGATACACAATCACTACTTATAAAACGCTATCAAATGCTCATCGTTACCATTTT
TATTACCCTATTCGGTTTACTGATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTCGAAGTATGAAGCAAATTTTAAGCAATGAATTTGAAACTGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTACAACGACAATATTTAAATACAGTTCGTGATTTGAATCACCACATTGAAATCGCCAC
AGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATTGAGCTATCGCTGGAAAAGAAAAAAACTGAAGAAA
AAAGTCGACAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATTCGTACCCCAATGAATGGCGTGATTGGTTTTACA
AATGTTTTATTGGAAAGCAAGCTGGACCCTTTACAACTGGACTACGTTAAAACGATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTTGATTGCATCCCGCTAGACATAA
GAGGTTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCGCACAAAAAAGGAATCGATTTAATCCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGATCATGGATACGTTCTTATACGCACTAAAATCGAGCAAGAAACAGATAAAGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGACACCAGCATC
ACACGCCGTTACGGTGGCTCAGGATTAGGCTTGGTTATATGTAAAAAACTATGTGAAGAAATGCATGGGCGTATTAGTCT
AACCAGTGAAATCAACAAAGGTTCTACTTTTAGCGCACGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCCCTCCATTTGGAAGCAATAGGTAATGGC
TTGGGATTTTGGGGTATAGAGGCTATACGCGTTGACTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAACGTCAATCAAGGATGTGAGCGACAAGCTGCTGAACTCATTGCCAAACACAAGCAAATTCCTT
TCGTGTTAATTTCCAAATGGCCTATTAATGATTTTGCGGCGCTTGGTGCTCGGGGTTTTCTTTACAAACCTATCAGCATC
CAAAAGCTTCAGGATCTGATTGAATCGATAGCCAATGAAAACCAAACTGAGAAAAATACGAACCAGGAACTGGATACTTT
ACGCGAACAGCTTCGTTTTCTTCATCCAGAGATACTGATTGCAGAAGACAACCCTGTCAATAAAATGCTATTAACATCCC
TATTAAACAATAATGCCAATATAACCACGGTTGACGATGGCGAAATGGCCGTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCATATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGTCAAAAATCCCTAATGAA
TAAACACTCTCCTATCGTTCTCATTACCGCCAGTAGCAGTGATCTGAGCTCCATCGATATGAAAAAATATGGAGTTGATT
TTTGTTTTCAAAAACCTATAGATGAAAAGCAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATTGATTGGCAATTATGCGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTTATAGAAGA
ATTATATAAGAATCGTGAAGAGTTTATTGGGTTAATGCATCAAAAAAACGTAAAGGGCCTGGCTGATTTGGCTCATAAAT
TACATGGCGCCTGTTGTTTTTGTGGCGTGCCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAGGCTTGCAAGACGAACC
GCTAATGCTGATAATTTAACCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTACTCACAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

• Hpt domain (Hpt) (819-899)

• Response regulator receiver domain (Response_reg) (678-787)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	99.341	100	0.993