Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACI8NS_RS01505 Genome accession   NZ_CP174125
Coordinates   292976..293620 (+) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain AX22     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 287976..298620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI8NS_RS01480 (ACI8NS_01480) - 288424..288765 (-) 342 WP_032876795.1 hypothetical protein -
  ACI8NS_RS01485 (ACI8NS_01485) degQ 289231..289371 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACI8NS_RS01490 (ACI8NS_01490) - 289579..290439 (+) 861 WP_142925231.1 polyprenyl synthetase family protein -
  ACI8NS_RS01495 (ACI8NS_01495) comX 290408..290581 (+) 174 WP_012118314.1 competence pheromone ComX -
  ACI8NS_RS01500 (ACI8NS_01500) comP 290595..292895 (+) 2301 WP_032876801.1 histidine kinase Regulator
  ACI8NS_RS01505 (ACI8NS_01505) comA 292976..293620 (+) 645 WP_003152052.1 response regulator transcription factor Regulator
  ACI8NS_RS01510 (ACI8NS_01510) - 293642..294025 (+) 384 WP_007613430.1 hotdog fold thioesterase -
  ACI8NS_RS01515 (ACI8NS_01515) mnhG 294065..294439 (-) 375 WP_007613429.1 monovalent cation/H(+) antiporter subunit G -
  ACI8NS_RS01520 (ACI8NS_01520) - 294423..294707 (-) 285 WP_017419420.1 Na(+)/H(+) antiporter subunit F1 -
  ACI8NS_RS01525 (ACI8NS_01525) - 294707..295183 (-) 477 WP_007613428.1 Na+/H+ antiporter subunit E -
  ACI8NS_RS01530 (ACI8NS_01530) - 295189..296670 (-) 1482 WP_032876804.1 Na+/H+ antiporter subunit D -
  ACI8NS_RS01535 (ACI8NS_01535) - 296663..297004 (-) 342 WP_032876807.1 Na(+)/H(+) antiporter subunit C -
  ACI8NS_RS01540 (ACI8NS_01540) - 297004..297435 (-) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=1074434 ACI8NS_RS01505 WP_003152052.1 292976..293620(+) (comA) [Bacillus velezensis strain AX22]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1074434 ACI8NS_RS01505 WP_003152052.1 292976..293620(+) (comA) [Bacillus velezensis strain AX22]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTTGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGTCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment