Detailed information NTG0107301

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACAM22_RS00230
• Genome accession: NZ_AP028929
• Coordinates: 42443..44875 (+)
• Length: 810 a.a.
• NCBI ID: WP_265471636.1
• Uniprot ID: A0AAT9FY82
• Organism: Streptococcus sp. SN-1
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 37443..49875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM22_RS00200 (MASAN616_00360)	cbpD	37712..38824 (+)	1113	WP_369606775.1	choline binding-anchored murein hydrolase CbpD	-
ACAM22_RS00205 (MASAN616_00370)	-	39079..39369 (+)	291	WP_261054738.1	thiamine-binding protein	-
ACAM22_RS00210 (MASAN616_00380)	-	39332..40090 (+)	759	WP_265471640.1	ABC transporter permease	-
ACAM22_RS00215 (MASAN616_00390)	-	40129..41136 (+)	1008	WP_265471639.1	ABC transporter substrate-binding protein	-
ACAM22_RS00220 (MASAN616_00400)	-	41136..41864 (+)	729	WP_265471638.1	ABC transporter ATP-binding protein	-
ACAM22_RS00225 (MASAN616_00410)	-	41983..42441 (+)	459	WP_265471637.1	CtsR family transcriptional regulator	-
ACAM22_RS00230 (MASAN616_00420)	clpC	42443..44875 (+)	2433	WP_265471636.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ACAM22_RS00235 (MASAN616_00430)	-	44948..45178 (-)	231	WP_265471635.1	hypothetical protein	-
ACAM22_RS00240 (MASAN616_00440)	-	45456..46154 (+)	699	WP_265471634.1	hypothetical protein	-
ACAM22_RS00245 (MASAN616_00450)	-	46224..46775 (-)	552	WP_369606776.1	cysteine hydrolase family protein	-
ACAM22_RS00250 (MASAN616_00460)	dusB	46777..47757 (-)	981	WP_025169901.1	tRNA dihydrouridine synthase DusB	-
ACAM22_RS00255 (MASAN616_00470)	hslO	47744..48616 (-)	873	WP_369606777.1	Hsp33 family molecular chaperone HslO	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90120.84 Da
• Isoelectric Point: 5.9311

>NTDB_id=107301 ACAM22_RS00230 WP_265471636.1 42443..44875(+) (clpC) [Streptococcus sp. SN-1]
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEIDRLEEVALELTETDYSQDETFTELPF
SHRLQVLFDEAEYVASVVHAKVLGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMAILQGLKVTYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSGLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLETELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKIGV
KAGQLKFDIA

Nucleotide

• Length: 2433 bp

>NTDB_id=107301 ACAM22_RS00230 WP_265471636.1 42443..44875(+) (clpC) [Streptococcus sp. SN-1]
ATGAACTATTCAAAAGCATTGAATGAATGTATTGAAAGTGCCTACATGGTTGCTGGCCATTTTGGAGCTCGTTACCTAGA
GTCTTGGCACTTGTTGATTGCCATGTCCAATCACAGTTATAGTGTGGCAGGGGCGACTTTAAATGATTATCCATATGAGA
TAGACCGTTTAGAAGAGGTGGCTTTGGAACTGACTGAAACGGACTATAGCCAGGATGAAACCTTTACGGAATTGCCGTTC
TCCCATCGTTTACAGGTTCTTTTTGATGAAGCGGAATATGTGGCGTCAGTGGTTCATGCTAAGGTGCTAGGGACAGAGCA
TGTCTTCTATGCGATTTTGCATGATGGTAATGCATTGGCAACTCGTATATTGGAAAGGGCAGGTTTTTCTTATGAAGACA
AGAAAGATCAGGTCAAGATTGCTGCACTTCGTCGAAATTTAGAAGAACGGGCAGGCTGGACTCGTGAAGACCTCAAGGCT
TTACGCCAACGCCATCGTACCGTAGCTGACAAGCAAAATTCTATGGCTAATATGATGGGAATGCCGCAGACTCCTAGTGG
TGGTCTCGAGGACTATACGCATGATTTGACAGAGCAAGCGCGTTCTGGCAAGTTGGAGCCAGTCATCGGTCGGGATAAGG
AAATCTCGCGTATGATTCAAATCTTGAGCCGGAAAACCAAGAATAATCCTGTCTTGGTTGGAGATGCGGGTGTCGGGAAA
ACAGCTCTGGCGCTTGGTCTTGCCCAGCGTATTGCTAGTGGGGATGTGCCTGCGGAAATGGCTAAGATGCGCGTGTTAGA
GCTTGATTTGATGAATGTCGTCGCAGGGACACGTTTCCGTGGTGACTTTGAAGAACGCATGAATAATATCATCAAGGATA
TTGAAGAAGATGGTCAAGTAATTCTATTTATCGACGAACTCCACACCATCATGGGTTCTGGGAGCGGGATTGATTCGACC
CTAGATGCGGCTAATATCTTGAAGCCAGCCTTGGCGCGTGGAACTTTGAGAACGGTTGGTGCCACCACTCAGGAAGAGTA
CCAAAAACACATTGAAAAAGACGCGGCCCTTTCTCGTCGTTTCGCCAAAGTGACGATTGAAGAGCCAAGTGTGGCCGACA
GTATGGCCATTTTGCAAGGTTTGAAGGTGACTTATGAGAAACATCACCGGGTGCAAATCACAGATGAAGCGGTTGAAACA
GCTGTCAAGATGGCTCATCGTTACTTGACTAGCCGTCACTTGCCAGACTCTGCTATCGATCTCTTGGACGAAGCAGCGGC
AACAGTGCAAAATAAGGCTAAGCATGTAAAAGCAGACGATTCAGGCTTGAGTCCAGCTGACAAGGCCTTGATGGATGGTA
AGTGGAAACAAGCGGCCCAGCTAATTGCAAAAGAAGAGGAAGTGCCTGTCTATAAAGACCTGGTGACAGAGTCTGATATT
TTGACTACCTTGAGTCGCTTGTCAGGTATCCCAGTTCAAAAATTGACTCAGACTGATGCTAAGAAATACCTGAATCTGGA
AACTGAATTGCACAAACGTGTCATCGGGCAAGATCAAGCTGTTTCAAGCATTAGCCGTGCGATTCGTCGCAACCAGTCAG
GGATTCGCAGTCATAAGCGTCCGATTGGTTCCTTTATGTTCTTAGGGCCTACAGGTGTCGGTAAGACCGAATTGGCCAAG
GCTCTGGCAGAAGTTCTTTTTGACGATGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTTGCAGC
CAGTCGTCTCAACGGAGCTCCTCCAGGCTATGTGGGTTATGAAGAAGGTGGGGAGTTGACTGAGAAGGTCCGCAACAAAC
CATACTCTGTTCTCCTCTTTGATGAGGTAGAGAAGGCCCATCCAGACATCTTTAATGTTCTCTTGCAGGTTCTGGATGAC
GGTGTATTGACTGATAGCAAGGGCCGCAAGGTCGACTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
AGCCCTTCGGGATGACAAGACAGTCGGCTTTGGAGCTAAGGATATCCGTTTTGACCAGGAAAATATGGAAAAACGTATGT
TTGAAGAGCTGAAAAAGGCTTACAGACCGGAGTTTATTAACCGTATTGATGAAAAGGTGGTCTTCCATAGCCTATCTAGC
GACCATATGCAGGAAGTGGTGAAGATTATGGTCAAACCTTTAGTGGCAAGTTTGGCTGAAAAAGGAATTGACTTGAAATT
ACAAGCTTCCGCACTGAAATTATTGGCAAATCAAGGATATGACCCAGAGATGGGAGCCCGTCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAGGACAAGTTGGCAGAACTTCTTCTTAAGGGAGATTTAGTGGCAGGCAGCACACTTAAGATTGGTGTC
AAAGCAGGCCAATTAAAATTTGATATTGCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (718-797)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

• AAA domain (Cdc48 subfamily) (AAA_2) (540-711)

• AAA lid domain (AAA_lid_9) (370-439)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-61)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (103-139)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	98.889	100	0.989
clpC	Streptococcus pneumoniae Rx1	98.889	100	0.989
clpC	Streptococcus pneumoniae D39	98.889	100	0.989
clpC	Streptococcus mutans UA159	66.913	100	0.672
clpC	Streptococcus thermophilus LMD-9	66.216	100	0.665
clpC	Streptococcus thermophilus LMG 18311	66.093	100	0.664
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.733	100	0.499
clpC	Bacillus subtilis subsp. subtilis str. 168	45.117	99.877	0.451
clpE	Streptococcus mutans UA159	49.194	76.543	0.377
clpE	Streptococcus pneumoniae Rx1	47.134	77.531	0.365
clpE	Streptococcus pneumoniae D39	47.134	77.531	0.365
clpE	Streptococcus pneumoniae R6	47.134	77.531	0.365
clpE	Streptococcus pneumoniae TIGR4	47.134	77.531	0.365