Detailed information NTG0107191

Bioinformatically predicted

Overview

• Name: vicX
• Type: Regulator
• Locus tag: AAA995_RS05860
• Genome accession: NZ_AP028877
• Coordinates: 1161371..1162180 (-)
• Length: 269 a.a.
• NCBI ID: WP_001289493.1
• Uniprot ID: Q9RCS5
• Organism: Streptococcus pneumoniae strain 21P20
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1160051..1161307	1161371..1162180	flank	64

Gene organization within MGE regions

Location: 1160051..1162180

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA995_RS05855 (SP21P20_11600)	-	1160051..1161307 (+)	1257	WP_000530083.1	ISL3 family transposase	-
AAA995_RS05860 (SP21P20_11610)	vicX	1161371..1162180 (-)	810	WP_001289493.1	MBL fold metallo-hydrolase	Regulator

Sequence

Protein

• Length: 269 a.a.
• Molecular weight: 29916.89 Da
• Isoelectric Point: 6.1743

>NTDB_id=107191 AAA995_RS05860 WP_001289493.1 1161371..1162180(-) (vicX) [Streptococcus pneumoniae strain 21P20]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide

• Length: 810 bp

>NTDB_id=107191 AAA995_RS05860 WP_001289493.1 1161371..1162180(-) (vicX) [Streptococcus pneumoniae strain 21P20]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTGGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGCAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACTTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGACAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (15-223)

3D structure

• AlphaFold DB: Q9RCS5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicX	Streptococcus mutans UA159	77.323	100	0.773