Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   ACIVIR_RS04470 Genome accession   NZ_CP173225
Coordinates   850629..851360 (+) Length   243 a.a.
NCBI ID   WP_050221198.1    Uniprot ID   A0AA44S718
Organism   Streptococcus pneumoniae strain 262     
Function   export ComS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 834334..859082 850629..851360 within 0


Gene organization within MGE regions


Location: 834334..859082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIVIR_RS04400 - 834334..835614 (+) 1281 WP_001220759.1 restriction endonuclease subunit S -
  ACIVIR_RS04405 psrA 835671..836468 (+) 798 WP_000651177.1 tyrosine-type DNA invertase PsrA -
  ACIVIR_RS04410 - 836479..837087 (+) 609 WP_000240090.1 restriction endonuclease subunit S -
  ACIVIR_RS04415 - 837035..838600 (-) 1566 WP_404361641.1 restriction endonuclease subunit S -
  ACIVIR_RS04420 - 838600..840063 (-) 1464 WP_054387359.1 class I SAM-dependent DNA methyltransferase -
  ACIVIR_RS04425 hsdR 840076..842409 (-) 2334 WP_054387360.1 EcoAI/FtnUII family type I restriction enzme subunit R -
  ACIVIR_RS04430 - 843017..843526 (+) 510 WP_054387361.1 DUF2812 domain-containing protein -
  ACIVIR_RS04435 hrcA 843690..844724 (+) 1035 WP_000255768.1 heat-inducible transcriptional repressor HrcA -
  ACIVIR_RS04440 grpE 844751..845275 (+) 525 WP_000046027.1 nucleotide exchange factor GrpE -
  ACIVIR_RS04445 dnaK 845755..847578 (+) 1824 WP_000034662.1 molecular chaperone DnaK -
  ACIVIR_RS04450 - 847580..847936 (+) 357 WP_000114433.1 hypothetical protein -
  ACIVIR_RS04455 dnaJ 848338..849474 (+) 1137 WP_050073039.1 molecular chaperone DnaJ -
  ACIVIR_RS04460 - 849854..850141 (-) 288 WP_000777760.1 hypothetical protein -
  ACIVIR_RS04465 - 850151..850561 (-) 411 WP_001278301.1 HIT family protein -
  ACIVIR_RS04470 pptA 850629..851360 (+) 732 WP_050221198.1 ABC transporter ATP-binding protein Regulator
  ACIVIR_RS04475 - 851357..852406 (+) 1050 WP_050221199.1 ABC transporter permease -
  ACIVIR_RS04480 - 852468..852797 (-) 330 WP_000132585.1 hypothetical protein -
  ACIVIR_RS04485 comE/blpR 853093..853830 (+) 738 WP_050221200.1 LytTR family DNA-binding domain-containing protein Regulator
  ACIVIR_RS04490 - 853844..855193 (+) 1350 WP_050221201.1 sensor histidine kinase -
  ACIVIR_RS04495 - 855427..855618 (+) 192 WP_376738204.1 hypothetical protein -
  ACIVIR_RS04500 - 855819..855983 (+) 165 WP_049511538.1 hypothetical protein -
  ACIVIR_RS04505 - 855980..856384 (+) 405 WP_050221203.1 hypothetical protein -
  ACIVIR_RS04510 - 856655..856931 (+) 277 Protein_845 immunity protein -
  ACIVIR_RS04515 - 857014..857397 (+) 384 WP_050221205.1 hypothetical protein -
  ACIVIR_RS04520 - 857462..858151 (+) 690 WP_050221206.1 CPBP family intramembrane glutamic endopeptidase -
  ACIVIR_RS04525 blpZ 858193..858441 (+) 249 WP_050221207.1 immunity protein BlpZ -
  ACIVIR_RS04530 - 858471..859082 (+) 612 WP_050221208.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27125.65 Da        Isoelectric Point: 4.8865

>NTDB_id=1070805 ACIVIR_RS04470 WP_050221198.1 850629..851360(+) (pptA) [Streptococcus pneumoniae strain 262]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININRLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL

Nucleotide


Download         Length: 732 bp        

>NTDB_id=1070805 ACIVIR_RS04470 WP_050221198.1 850629..851360(+) (pptA) [Streptococcus pneumoniae strain 262]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGTTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATCGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAAATGTTCCGTTTGGAACAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTGGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAAAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGTGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACCAAAGAG
GAGGATCTATGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

71.784

99.177

0.712
  pptA Streptococcus thermophilus LMD-9

70.954

99.177

0.704

Multiple sequence alignment