Detailed information NTG1070526

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACIQTD_RS11595
• Genome accession: NZ_CP173185
• Coordinates: 2378067..2379095 (-)
• Length: 342 a.a.
• NCBI ID: WP_058217736.1
• Uniprot ID: A0AB35KFG0
• Organism: Lactococcus lactis subsp. lactis strain MGEL24009
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2373067..2384095

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIQTD_RS11565	-	2373354..2373851 (-)	498	WP_003132662.1	nitroreductase family protein	-
ACIQTD_RS11570	-	2373838..2374047 (-)	210	WP_003132661.1	hypothetical protein	-
ACIQTD_RS11575	-	2374044..2374871 (-)	828	WP_026138971.1	radical SAM protein	-
ACIQTD_RS11580	-	2374864..2376063 (-)	1200	WP_017865175.1	MFS transporter	-
ACIQTD_RS11585	-	2376060..2376905 (-)	846	WP_235586059.1	radical SAM protein	-
ACIQTD_RS11590	-	2377089..2377946 (-)	858	WP_058217737.1	Rgg/GadR/MutR family transcriptional regulator	-
ACIQTD_RS11595	sepM	2378067..2379095 (-)	1029	WP_058217736.1	SepM family pheromone-processing serine protease	Regulator
ACIQTD_RS11600	coaD	2379082..2379579 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
ACIQTD_RS11605	rsmD	2379627..2380166 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACIQTD_RS11610	-	2380337..2381557 (-)	1221	WP_081200148.1	MFS transporter	-
ACIQTD_RS11615	lmrP	2381641..2382867 (-)	1227	WP_012898648.1	multidrug efflux MFS transporter LmrP	-
ACIQTD_RS11620	-	2383055..2383549 (+)	495	WP_058217733.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37365.98 Da
• Isoelectric Point: 9.8679

>NTDB_id=1070526 ACIQTD_RS11595 WP_058217736.1 2378067..2379095(-) (sepM) [Lactococcus lactis subsp. lactis strain MGEL24009]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNMLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKNIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=1070526 ACIQTD_RS11595 WP_058217736.1 2378067..2379095(-) (sepM) [Lactococcus lactis subsp. lactis strain MGEL24009]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATATGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAAATATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (228-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.986	100	0.494