Detailed information NTG1069116

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACF1RT_RS09440
• Genome accession: NZ_CP172847
• Coordinates: 1887072..1889513 (-)
• Length: 813 a.a.
• NCBI ID: WP_002269598.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain DPC6143
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1882072..1894513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF1RT_RS09425 (ACF1RT_09425)	rpsJ	1882896..1883204 (-)	309	WP_002262341.1	30S ribosomal protein S10	-
ACF1RT_RS09430 (ACF1RT_09430)	-	1883524..1884210 (+)	687	WP_002266894.1	S24 family peptidase	-
ACF1RT_RS09435 (ACF1RT_09435)	-	1884401..1886788 (-)	2388	WP_002293225.1	glycoside hydrolase family 68 protein	-
ACF1RT_RS09440 (ACF1RT_09440)	clpC	1887072..1889513 (-)	2442	WP_002269598.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ACF1RT_RS09445 (ACF1RT_09445)	ctsR	1889510..1889974 (-)	465	WP_002262345.1	transcriptional regulator CtsR	-
ACF1RT_RS09450 (ACF1RT_09450)	tsf	1890257..1891303 (-)	1047	WP_002275712.1	translation elongation factor Ts	-
ACF1RT_RS09455 (ACF1RT_09455)	rpsB	1891370..1892155 (-)	786	WP_002262347.1	30S ribosomal protein S2	-
ACF1RT_RS09460 (ACF1RT_09460)	-	1892345..1894197 (-)	1853	Protein_1813	hypothetical protein	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90298.07 Da
• Isoelectric Point: 6.9065

>NTDB_id=1069116 ACF1RT_RS09440 WP_002269598.1 1887072..1889513(-) (clpC) [Streptococcus mutans strain DPC6143]
MTDYSLKMQEVFRLAQFEAARFESSYLESWHVLLAMVEIDSSVAGLSFAEFEADVRFEDYQAAAILAIGKKPKSSSNDIM
LLEQSHALKRTLAEAAAISQVTHAKEVGTEHVLFAMLLNPNLLATRILELVGFHAKDDGESIRLLDLRKVIERYAGFSKE
DIKAIFEMRKPKKVKNSSSFSDLMKPPSVTGELADFTRDLTELARQGRLEPVIGREQEISRIVQILSRKTKNNPVLVGDA
GVGKTALAYGLAQRIVDSAVPFELADMKVLELDMMSVVAGTRFRGDFEERMNQIIADIEADGHIVLFIDELHTIMGSGSG
IDSTLDAANILKPALARGSLRTIGATTQEEYQKHIEKDAALSRRFAKVTIEEPSEEEAYQILLGLKKSYETYHHVIISDA
AVMAAVKGAHRYLSGKNLPDSAIDLLDEASATVQGLVKKKAPAYLTDLDHALITNDYQLAKRLLKKEKKPLLKKRAEVKE
EDILATLSKLSGIPVKKLTQADSKKYLNLERELHKRVIGQDDAVSSISRAIRRNQSGIRVGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKSFSQDYKAMESRILEELKKVYRPEFINRIDEKVVFHN
LGQEDIRHVVKIMVAPLIAHLADQGITLKFQPSALKHLALAGYDAEMGARPLRRTLQTEVEDKLAELILSGKLASGQTLK
IGIQKEKLKFDIV

Nucleotide

• Length: 2442 bp

>NTDB_id=1069116 ACF1RT_RS09440 WP_002269598.1 1887072..1889513(-) (clpC) [Streptococcus mutans strain DPC6143]
ATGACCGATTACTCATTAAAAATGCAGGAAGTCTTTCGATTGGCGCAGTTTGAAGCAGCTCGTTTTGAAAGTTCCTATTT
AGAAAGCTGGCATGTCCTTCTTGCAATGGTAGAGATTGATTCCTCAGTGGCTGGTTTAAGTTTTGCGGAGTTTGAAGCAG
ATGTCCGTTTTGAGGATTATCAGGCTGCTGCTATTTTGGCGATTGGTAAAAAGCCTAAGTCCTCGAGTAATGATATTATG
CTTTTAGAGCAATCACATGCTTTAAAACGAACCCTAGCAGAGGCCGCTGCTATTAGTCAGGTGACACACGCTAAAGAAGT
CGGCACAGAACATGTTCTCTTTGCTATGTTACTGAATCCTAATCTTTTGGCGACTCGCATTTTAGAATTAGTTGGTTTTC
ACGCCAAAGATGATGGAGAGTCCATCCGTCTTTTGGATCTGCGAAAAGTGATTGAACGTTATGCTGGCTTTTCCAAAGAG
GACATTAAGGCCATCTTTGAAATGCGTAAACCTAAAAAGGTCAAAAATAGCAGCAGCTTTTCTGATTTAATGAAGCCACC
TAGCGTTACAGGTGAACTAGCTGATTTTACACGGGATTTGACGGAGTTGGCAAGACAAGGTCGTTTAGAACCTGTTATTG
GCCGTGAACAAGAAATTTCACGGATAGTTCAAATTTTAAGCCGTAAGACAAAAAATAACCCTGTTTTAGTTGGCGATGCT
GGTGTTGGGAAGACGGCCTTGGCTTACGGCCTTGCTCAACGTATTGTGGATAGTGCCGTTCCTTTTGAATTGGCAGATAT
GAAAGTACTAGAGCTCGATATGATGAGTGTTGTTGCAGGGACTCGTTTTCGTGGCGATTTTGAGGAACGAATGAATCAAA
TTATTGCAGACATTGAAGCAGATGGTCACATTGTCCTCTTCATTGATGAGCTGCATACCATTATGGGTTCAGGAAGTGGT
ATTGATAGTACGCTGGATGCTGCTAATATTCTTAAACCAGCTTTAGCGCGCGGCAGTCTTAGAACGATTGGAGCGACTAC
TCAAGAGGAGTATCAAAAGCATATTGAAAAAGATGCTGCTCTTTCTCGCCGTTTTGCTAAGGTAACTATTGAAGAACCAA
GTGAAGAAGAAGCTTATCAGATCTTGCTTGGTTTAAAGAAAAGTTATGAAACTTATCATCATGTTATTATTTCTGATGCA
GCCGTAATGGCGGCAGTCAAAGGAGCACATCGTTATTTAAGTGGTAAAAATTTACCTGATTCGGCTATCGATCTTTTAGA
TGAAGCTAGTGCAACTGTTCAAGGCTTAGTGAAAAAAAAGGCACCAGCTTATTTGACAGATTTAGATCATGCTCTTATCA
CTAACGATTACCAATTAGCTAAGCGTTTGCTGAAAAAGGAGAAGAAGCCTCTACTTAAAAAACGAGCTGAAGTCAAGGAA
GAAGATATCCTAGCTACTCTCAGCAAACTTTCAGGCATCCCTGTCAAAAAATTAACACAGGCTGACAGTAAAAAGTACCT
TAATCTCGAAAGGGAATTACATAAGCGTGTAATTGGTCAAGACGATGCGGTGTCCAGTATCAGCCGTGCTATTCGCCGCA
ATCAATCCGGAATTCGGGTTGGCAAACGTCCCATTGGCTCTTTCATGTTTTTGGGGCCGACAGGTGTTGGTAAAACAGAG
CTTGCTAAGGCTTTGGCAGAAGTGCTTTTTGATGATGAGTCAGCTCTTATTCGTTTTGACATGAGCGAATATATGGAAAA
ATTTGCAGCTTCTCGCCTTAATGGAGCTCCTCCGGGCTATGTGGGGTATGAAGAAGGCGGTGAGTTGACGGAAAAGGTTC
GTAACAAACCTTACTCTGTTCTTCTTTTTGATGAGGTGGAAAAAGCTCATCCAGATATTTTCAATATCTTACTTCAAGTA
CTTGATGATGGTGTTTTGACAGATAGCCGTGGTCGCAAAGTTGATTTTTCAAATACGATTATTATCATGACCTCTAATTT
GGGTGCGACTGCGCTTCGTGATGATAAAACCGTTGGTTTTGGAGCTAAAAGCTTTTCCCAGGATTATAAGGCCATGGAAA
GTCGTATTTTAGAGGAATTAAAAAAGGTTTACCGACCTGAATTTATTAATCGTATTGATGAAAAAGTTGTCTTTCATAAC
CTTGGTCAAGAAGACATACGCCATGTTGTTAAAATTATGGTTGCTCCATTGATTGCCCATTTGGCTGATCAGGGGATTAC
ACTTAAGTTTCAGCCTTCAGCTTTGAAACATTTAGCTCTGGCAGGTTATGATGCTGAAATGGGGGCACGTCCTTTGCGTC
GGACACTTCAGACAGAAGTGGAAGATAAGTTAGCAGAGCTTATTCTTTCGGGAAAACTAGCTAGTGGACAGACTCTGAAA
ATAGGTATTCAAAAAGAAAAATTAAAATTTGATATTGTATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-55)

• AAA lid domain (AAA_lid_9) (374-461)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-366)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	99.754	100	0.998
clpC	Streptococcus thermophilus LMD-9	72.304	100	0.726
clpC	Streptococcus thermophilus LMG 18311	72.181	100	0.724
clpC	Streptococcus pneumoniae TIGR4	66.953	100	0.67
clpC	Streptococcus pneumoniae Rx1	66.953	100	0.67
clpC	Streptococcus pneumoniae D39	66.953	100	0.67
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.98	100	0.502
clpC	Bacillus subtilis subsp. subtilis str. 168	43.705	100	0.444
clpE	Streptococcus pneumoniae TIGR4	47.2	76.876	0.363
clpE	Streptococcus pneumoniae Rx1	47.2	76.876	0.363
clpE	Streptococcus pneumoniae D39	47.2	76.876	0.363
clpE	Streptococcus pneumoniae R6	47.2	76.876	0.363
clpE	Streptococcus mutans UA159	47.04	76.876	0.362