Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACFMPA_RS06245 Genome accession   NZ_CP172605
Coordinates   1206637..1207293 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus sp. SG20032     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1201637..1212293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFMPA_RS06215 (ACFMPA_06215) oppF 1202102..1203019 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACFMPA_RS06220 (ACFMPA_06220) - 1203126..1204343 (+) 1218 WP_167408195.1 MFS transporter -
  ACFMPA_RS06225 (ACFMPA_06225) - 1204507..1205085 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACFMPA_RS06230 (ACFMPA_06230) spx 1205266..1205661 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ACFMPA_RS06235 (ACFMPA_06235) - 1205704..1206360 (-) 657 WP_003232944.1 TerC family protein -
  ACFMPA_RS06240 (ACFMPA_06240) - 1206530..1206670 (+) 141 WP_119122854.1 hypothetical protein -
  ACFMPA_RS06245 (ACFMPA_06245) mecA 1206637..1207293 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  ACFMPA_RS06250 (ACFMPA_06250) - 1207288..1207410 (-) 123 WP_021479547.1 hypothetical protein -
  ACFMPA_RS06255 (ACFMPA_06255) coiA 1207454..1208605 (+) 1152 WP_208476220.1 competence protein CoiA Machinery gene
  ACFMPA_RS06260 (ACFMPA_06260) pepF 1208835..1210664 (+) 1830 WP_167408054.1 oligoendopeptidase F -
  ACFMPA_RS06265 (ACFMPA_06265) - 1210702..1210869 (-) 168 WP_003244944.1 hypothetical protein -
  ACFMPA_RS06270 (ACFMPA_06270) spxH 1211183..1212082 (-) 900 WP_024573348.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=1068209 ACFMPA_RS06245 WP_003232942.1 1206637..1207293(+) (mecA) [Bacillus sp. SG20032]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1068209 ACFMPA_RS06245 WP_003232942.1 1206637..1207293(+) (mecA) [Bacillus sp. SG20032]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTTGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment