Detailed information NTG1067764

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACH5DO_RS11525
• Genome accession: NZ_CP172432
• Coordinates: 2392477..2393520 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain DG29
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2387477..2398520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACH5DO_RS11495 (ACH5DO_11495)	-	2388092..2388202 (+)	111	WP_014937049.1	hypothetical protein	-
ACH5DO_RS11500 (ACH5DO_11500)	-	2388231..2388644 (+)	414	WP_025174370.1	hypothetical protein	-
ACH5DO_RS11505 (ACH5DO_11505)	-	2388833..2389819 (-)	987	WP_000999712.1	aromatic acid exporter family protein	-
ACH5DO_RS11510 (ACH5DO_11510)	map	2390403..2391161 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
ACH5DO_RS11515 (ACH5DO_11515)	-	2391378..2391764 (+)	387	WP_001110182.1	hypothetical protein	-
ACH5DO_RS11520 (ACH5DO_11520)	liaF	2391779..2392480 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACH5DO_RS11525 (ACH5DO_11525)	vraS	2392477..2393520 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACH5DO_RS11530 (ACH5DO_11530)	vraR	2393510..2394139 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACH5DO_RS11535 (ACH5DO_11535)	-	2394252..2395469 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACH5DO_RS11540 (ACH5DO_11540)	-	2395747..2396022 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
ACH5DO_RS11545 (ACH5DO_11545)	-	2396029..2396493 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACH5DO_RS11550 (ACH5DO_11550)	-	2396640..2396840 (+)	201	WP_000180460.1	DUF1128 family protein	-
ACH5DO_RS11555 (ACH5DO_11555)	-	2396843..2398099 (+)	1257	WP_074347694.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1067764 ACH5DO_RS11525 WP_001017131.1 2392477..2393520(+) (vraS) [Staphylococcus aureus strain DG29]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1067764 ACH5DO_RS11525 WP_001017131.1 2392477..2393520(+) (vraS) [Staphylococcus aureus strain DG29]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1