Detailed information NTG1067680

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACFSN5_RS07875
• Genome accession: NZ_CP172427
• Coordinates: 1719331..1721619 (+)
• Length: 762 a.a.
• NCBI ID: WP_165211360.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZJ 1593
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1714331..1726619

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFSN5_RS07855 (ACFSN5_07855)	-	1714443..1715135 (-)	693	WP_165211351.1	amino acid ABC transporter permease	-
ACFSN5_RS07860 (ACFSN5_07860)	adhP	1715743..1716765 (-)	1023	WP_165211354.1	alcohol dehydrogenase AdhP	-
ACFSN5_RS07865 (ACFSN5_07865)	-	1717662..1717892 (-)	231	WP_004228013.1	DUF1797 family protein	-
ACFSN5_RS07870 (ACFSN5_07870)	argF	1718146..1719111 (-)	966	WP_165211357.1	ornithine carbamoyltransferase	-
ACFSN5_RS07875 (ACFSN5_07875)	clpE	1719331..1721619 (+)	2289	WP_165211360.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ACFSN5_RS07880 (ACFSN5_07880)	-	1722101..1722553 (+)	453	WP_165211363.1	NUDIX hydrolase	-
ACFSN5_RS07885 (ACFSN5_07885)	-	1722620..1722922 (+)	303	WP_165211366.1	DUF1827 family protein	-
ACFSN5_RS07890 (ACFSN5_07890)	ileS	1723027..1725822 (-)	2796	WP_165329379.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 762 a.a.
• Molecular weight: 84805.86 Da
• Isoelectric Point: 4.9075

>NTDB_id=1067680 ACFSN5_RS07875 WP_165211360.1 1719331..1721619(+) (clpE) [Streptococcus sp. ZJ 1593]
MLCQNCKLNDASIHLYANVNGQQKQIDLCQNCYRIMKADPENILNSNLTSQNPQNQSMDSFFDDFFGDLNNFRAFNPDLP
NSPQTQAGRDGGNRGGNNGGANRGRRSQAQPQQPEGILEEFGINITDMARRGDIDPVIGRDQEIVRVIEILNRRTKNNPV
LIGEPGVGKTAVVEGLAQKIVDGNVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIV
GAGGTTDGSMDAGNILKPALARGDLQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILRGIQPKYQDYHHVK
YTDDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLVEAENLKAQATREEDFEKAAYFRDQIA
KYKEMQSQQLDEQDIPVITEKHIEAIVEEKTNIPVGNLKEKEQSQLVNLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGA
PNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVSKLVGAPPGYVGYEEAGQLTEKVRRNPYSL
ILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELSNFFSPE
FMNRFDGIIEFKALSKENLLHIVDLMLDDVNQRLSSNDLHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEYIEDAITDF
YLENPSEKNFKAVMASNGKISIKAAKKAEANIASKEESSSTD

Nucleotide

• Length: 2289 bp

>NTDB_id=1067680 ACFSN5_RS07875 WP_165211360.1 1719331..1721619(+) (clpE) [Streptococcus sp. ZJ 1593]
ATGTTATGTCAAAATTGTAAGCTCAACGATGCGAGCATACATCTCTATGCAAACGTTAATGGTCAGCAAAAGCAGATTGA
TCTCTGTCAAAACTGCTACCGAATTATGAAAGCTGATCCAGAAAATATTCTCAACAGTAATTTAACTAGCCAAAATCCAC
AGAATCAATCCATGGATTCTTTCTTTGATGATTTCTTTGGCGATTTAAACAACTTCAGGGCTTTTAACCCAGACTTGCCT
AATTCCCCACAAACACAGGCAGGACGCGATGGTGGTAACCGTGGAGGCAATAATGGTGGAGCTAATAGGGGACGTCGTTC
TCAGGCTCAGCCTCAGCAACCCGAAGGTATCTTGGAGGAGTTTGGTATCAATATTACTGATATGGCCCGTCGTGGCGATA
TCGATCCTGTCATCGGCCGCGATCAGGAAATTGTCCGCGTCATTGAAATCCTCAACCGGCGGACCAAGAATAATCCTGTC
CTAATTGGTGAACCTGGTGTTGGTAAAACCGCTGTTGTTGAAGGCCTAGCGCAAAAGATCGTTGATGGTAATGTGCCACA
AAAATTGCAGAGCAAGCAGGTTATCCGCTTGGATGTGGTCAGCTTGGTTCAAGGAACTGGTATCCGAGGTCAATTTGAAG
AGCGCATGCAAAAGCTAATGGAAGAAATTCGCCAGCGGCAAGATGTTATTCTTTTCATTGACGAAATCCATGAAATCGTA
GGTGCTGGTGGTACAACAGATGGCAGCATGGATGCTGGTAATATCTTAAAGCCAGCCCTAGCTCGCGGTGATCTGCAACT
GGTTGGAGCAACTACCCTCAATGAATATCGTATCATCGAAAAAGATGCCGCTCTGGAACGACGAATGCAGCCTGTCAAGG
TAGATGAGCCTTCTGTGGAAGAAACTATCACTATTTTGCGTGGTATTCAGCCAAAATATCAAGACTATCACCATGTTAAA
TACACCGATGACGCTATTGAAGCTGCTGCCGTCCTCTCTAACCGTTATATCCAAGACCGTTTCTTGCCGGATAAAGCTAT
CGATCTTTTGGATGAAGCTGGCTCAAAGATGAACTTGACTCTTAATTTTGTTGATCCTAAAGAAATTGACAAAAGGTTGG
TGGAAGCTGAGAATCTCAAGGCCCAAGCCACTCGTGAAGAAGATTTTGAAAAAGCAGCTTACTTCCGCGATCAAATCGCT
AAATATAAGGAAATGCAGTCCCAACAGCTGGATGAGCAAGATATTCCTGTCATCACCGAAAAACATATTGAAGCCATTGT
TGAAGAAAAAACCAATATTCCAGTAGGTAATCTCAAAGAAAAAGAGCAGTCTCAACTGGTTAATCTAGCTAGTGACCTCA
AGGCTCACGTTATCGGTCAAGACGATGCTGTTGATAAGATTGCTAAGGCCATCCGTCGAAATCGTGTTGGTTTGGGTGCT
CCCAATCGGCCAATCGGTAGCTTCCTCTTTGTCGGACCTACCGGTGTTGGTAAGACAGAACTGTCTAAACAATTGGCTAT
TGAGCTCTTCGGTTCAGCCGACAGCATGATTCGCTTTGATATGTCGGAATACATGGAAAAACACGCTGTGTCCAAATTGG
TCGGTGCCCCTCCAGGATATGTTGGCTATGAAGAAGCTGGGCAATTAACCGAAAAGGTTCGTCGCAATCCTTACTCCCTC
ATCCTCCTAGATGAAGTTGAAAAGGCTCATCCTGATGTTATGCACATGTTCCTGCAAGTCTTGGATGATGGTCGTCTGAC
AGATGGTCAAGGCCGGACTGTTAGCTTCAAGGATACCATTATTATCATGACCTCTAATGCTGGTACTGGTAAAGCAGAAG
CTTCTGTTGGTTTTGGAGCGGCCCGTGAAGGTCGGACCAACTCTGTCCTTGGCGAACTCAGTAACTTCTTCAGTCCAGAA
TTCATGAACCGTTTTGATGGTATTATTGAATTCAAGGCCTTGAGTAAGGAAAATCTGCTTCATATCGTTGACCTGATGCT
AGACGATGTCAATCAGCGTCTGTCCAGCAATGATCTCCACCTTGATGTAACGGATAAAGTTAAAGAAAAATTAGTTGATC
TGGGTTATGATCCTAAGATGGGAGCAAGGCCTTTGCGTCGAACGATTCAAGAGTATATTGAAGATGCGATCACTGACTTT
TATTTGGAAAATCCAAGTGAAAAGAACTTTAAAGCTGTCATGGCCTCAAATGGTAAGATTAGCATTAAGGCTGCTAAAAA
AGCTGAGGCAAACATCGCCAGTAAGGAAGAAAGTTCTTCTACAGACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (298-395)

• ATPase family associated with various cellular activities (AAA) (AAA) (160-273)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (654-729)

• AAA domain (Cdc48 subfamily) (AAA_2) (483-646)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.953	98.556	0.837
clpE	Streptococcus pneumoniae Rx1	82.166	99.344	0.816
clpE	Streptococcus pneumoniae D39	82.166	99.344	0.816
clpE	Streptococcus pneumoniae R6	82.166	99.344	0.816
clpE	Streptococcus pneumoniae TIGR4	82.166	99.344	0.816
clpC	Lactococcus lactis subsp. cremoris KW2	75.918	96.457	0.732
clpC	Bacillus subtilis subsp. subtilis str. 168	52.446	85.827	0.45
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.685	85.039	0.406
clpC	Streptococcus pneumoniae TIGR4	46.451	85.039	0.395
clpC	Streptococcus pneumoniae Rx1	46.451	85.039	0.395
clpC	Streptococcus pneumoniae D39	46.451	85.039	0.395
clpC	Streptococcus mutans UA159	47.115	81.89	0.386
clpC	Streptococcus thermophilus LMD-9	46.538	81.496	0.379
clpC	Streptococcus thermophilus LMG 18311	46.463	81.627	0.379