Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   ACHZEV_RS13470 Genome accession   NZ_CP172401
Coordinates   2759155..2760225 (+) Length   356 a.a.
NCBI ID   WP_000776425.1    Uniprot ID   -
Organism   Staphylococcus aureus strain M22.2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2754155..2765225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHZEV_RS13440 (ACHZEV_13440) - 2754578..2756041 (+) 1464 WP_001017856.1 rhomboid family intramembrane serine protease -
  ACHZEV_RS13445 (ACHZEV_13445) - 2756022..2756225 (+) 204 WP_316133276.1 YqgQ family protein -
  ACHZEV_RS13450 (ACHZEV_13450) - 2756222..2757208 (+) 987 WP_000161315.1 ROK family glucokinase -
  ACHZEV_RS13455 (ACHZEV_13455) - 2757208..2757537 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  ACHZEV_RS13460 (ACHZEV_13460) - 2757534..2758157 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  ACHZEV_RS13465 (ACHZEV_13465) comGA 2758209..2759183 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  ACHZEV_RS13470 (ACHZEV_13470) comGB 2759155..2760225 (+) 1071 WP_000776425.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACHZEV_RS13475 (ACHZEV_13475) comGC 2760239..2760550 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  ACHZEV_RS13480 (ACHZEV_13480) comGD 2760528..2760974 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACHZEV_RS13485 (ACHZEV_13485) comGE 2760961..2761260 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  ACHZEV_RS13490 (ACHZEV_13490) comGF 2761178..2761675 (+) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACHZEV_RS13495 (ACHZEV_13495) - 2761772..2761918 (+) 147 WP_001789879.1 hypothetical protein -
  ACHZEV_RS13500 (ACHZEV_13500) - 2761908..2762432 (+) 525 WP_001015120.1 shikimate kinase -
  ACHZEV_RS13505 (ACHZEV_13505) gcvT 2762591..2763682 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  ACHZEV_RS13510 (ACHZEV_13510) gcvPA 2763702..2765048 (+) 1347 WP_000019698.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41489.97 Da        Isoelectric Point: 10.1030

>NTDB_id=1067371 ACHZEV_RS13470 WP_000776425.1 2759155..2760225(+) (comGB) [Staphylococcus aureus strain M22.2]
MKLQWINTFKLHSKKRQLSKVQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNKLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=1067371 ACHZEV_RS13470 WP_000776425.1 2759155..2760225(+) (comGB) [Staphylococcus aureus strain M22.2]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGTCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGCACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAACCAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATCATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTCTCTATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAAATTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CGGGTTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTACCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGAAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.438

100

0.994
  comGB Staphylococcus aureus N315

99.438

100

0.994

Multiple sequence alignment