Detailed information NTG1067353

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACHZEV_RS07980
• Genome accession: NZ_CP172401
• Coordinates: 1694325..1695212 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain M22.2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1689325..1700212

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACHZEV_RS07950 (ACHZEV_07950)	-	1690058..1690819 (+)	762	WP_316133318.1	alpha/beta hydrolase family protein	-
ACHZEV_RS07955 (ACHZEV_07955)	-	1691063..1691518 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACHZEV_RS07960 (ACHZEV_07960)	-	1691640..1691741 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACHZEV_RS07965 (ACHZEV_07965)	-	1691801..1693225 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACHZEV_RS07970 (ACHZEV_07970)	-	1693423..1693623 (+)	201	WP_000604731.1	hypothetical protein	-
ACHZEV_RS07975 (ACHZEV_07975)	braR	1693649..1694314 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACHZEV_RS07980 (ACHZEV_07980)	braS	1694325..1695212 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACHZEV_RS07985 (ACHZEV_07985)	-	1695320..1696075 (+)	756	WP_316133317.1	ABC transporter ATP-binding protein	-
ACHZEV_RS07990 (ACHZEV_07990)	-	1696072..1698072 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACHZEV_RS07995 (ACHZEV_07995)	-	1698741..1698854 (+)	114	WP_014937089.1	hypothetical protein	-
ACHZEV_RS08000 (ACHZEV_08000)	-	1699236..1699496 (+)	261	WP_014937088.1	hypothetical protein	-
ACHZEV_RS08005 (ACHZEV_08005)	-	1699506..1700003 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACHZEV_RS08010 (ACHZEV_08010)	-	1700111..1700203 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1067353 ACHZEV_RS07980 WP_000143420.1 1694325..1695212(+) (braS) [Staphylococcus aureus strain M22.2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1067353 ACHZEV_RS07980 WP_000143420.1 1694325..1695212(+) (braS) [Staphylococcus aureus strain M22.2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993