Detailed information NTG1066919

Bioinformatically predicted

Overview

• Name: waaF
• Type: Regulator
• Locus tag: ACH6FJ_RS05945
• Genome accession: NZ_CP172372
• Coordinates: 1124312..1125271 (+)
• Length: 319 a.a.
• NCBI ID: WP_002852903.1
• Uniprot ID: A0A5Y6P8U5
• Organism: Campylobacter jejuni strain YH018
• Function: repress natural transformation (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1105700..1129316	1124312..1125271	within	0

Gene organization within MGE regions

Location: 1105700..1129316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACH6FJ_RS05845 (ACH6FJ_05835)	pglI	1105700..1106629 (-)	930	WP_002852770.1	GalNAc(5)-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase	-
ACH6FJ_RS05850 (ACH6FJ_05840)	pglH	1106622..1107701 (-)	1080	WP_079264866.1	GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)- diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase	-
ACH6FJ_RS05855 (ACH6FJ_05845)	pglK	1107698..1109392 (-)	1695	WP_002858308.1	ABC-type lipopolysaccharide transporter PglK	-
ACH6FJ_RS05860 (ACH6FJ_05850)	galE	1109386..1110372 (-)	987	WP_002893768.1	UDP-glucose 4-epimerase GalE	-
ACH6FJ_RS05865 (ACH6FJ_05855)	-	1110430..1111224 (-)	795	WP_002893767.1	3'-5' exonuclease	-
ACH6FJ_RS05870 (ACH6FJ_05860)	waaC	1111290..1112318 (+)	1029	WP_002893766.1	lipopolysaccharide heptosyltransferase I	-
ACH6FJ_RS05875 (ACH6FJ_05865)	htrB	1112308..1113195 (+)	888	WP_002893765.1	lipid A biosynthesis lauroyl acyltransferase HtrB	-
ACH6FJ_RS05880 (ACH6FJ_05870)	-	1113192..1114739 (+)	1548	WP_002930852.1	glycosyltransferase	-
ACH6FJ_RS05885 (ACH6FJ_05875)	-	1114743..1115927 (+)	1185	WP_002907417.1	glycosyltransferase family 2 protein	-
ACH6FJ_RS05890 (ACH6FJ_05880)	-	1115983..1117038 (+)	1056	WP_039332959.1	beta-1,4-N-acetylgalactosaminyltransferase	-
ACH6FJ_RS05895 (ACH6FJ_05885)	-	1117010..1117903 (-)	894	WP_002871710.1	glycosyltransferase family 2 protein	-
ACH6FJ_RS05900 (ACH6FJ_05890)	-	1117992..1118867 (+)	876	WP_002918311.1	alpha-2,3-sialyltransferase	-
ACH6FJ_RS05905 (ACH6FJ_05895)	neuB	1118868..1119908 (+)	1041	WP_002871708.1	N-acetylneuraminate synthase	-
ACH6FJ_RS05910 (ACH6FJ_05900)	neuC	1119905..1121029 (+)	1125	WP_395766157.1	UDP-N-acetylglucosamine 2-epimerase	-
ACH6FJ_RS05915 (ACH6FJ_05905)	-	1121022..1121645 (+)	624	WP_172669974.1	glycosyltransferase	-
ACH6FJ_RS05920 (ACH6FJ_05910)	-	1121638..1121970 (+)	333	WP_019260376.1	hypothetical protein	-
ACH6FJ_RS05925 (ACH6FJ_05915)	-	1121967..1122632 (+)	666	WP_002871705.1	cytidylyltransferase domain-containing protein	-
ACH6FJ_RS05930 (ACH6FJ_05920)	-	1122620..1122793 (+)	174	WP_002896733.1	hypothetical protein	-
ACH6FJ_RS05935 (ACH6FJ_05925)	-	1122919..1123449 (+)	531	WP_002922940.1	CatB-related O-acetyltransferase	-
ACH6FJ_RS05940 (ACH6FJ_05930)	waaV	1123441..1124253 (-)	813	WP_039332971.1	glycosyltransferase family 2 protein	-
ACH6FJ_RS05945 (ACH6FJ_05935)	waaF	1124312..1125271 (+)	960	WP_002852903.1	lipopolysaccharide heptosyltransferase II	Regulator
ACH6FJ_RS05950 (ACH6FJ_05940)	gmhA	1125252..1125812 (-)	561	WP_002869012.1	D-sedoheptulose 7-phosphate isomerase	-
ACH6FJ_RS05955 (ACH6FJ_05945)	rfaE1	1125809..1127194 (-)	1386	WP_052853943.1	D-glycero-beta-D-manno-heptose-7-phosphate kinase	-
ACH6FJ_RS05960 (ACH6FJ_05950)	rfaD	1127187..1128140 (-)	954	WP_052802041.1	ADP-glyceromanno-heptose 6-epimerase	-
ACH6FJ_RS05965 (ACH6FJ_05955)	gmhB	1128142..1128703 (-)	562	Protein_1155	D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase	-
ACH6FJ_RS05970 (ACH6FJ_05960)	-	1128785..1129087 (+)	303	WP_002852762.1	cytochrome c	-
ACH6FJ_RS05975 (ACH6FJ_05965)	ccoS	1129110..1129316 (-)	207	WP_002852798.1	cbb3-type cytochrome oxidase assembly protein CcoS	-

Sequence

Protein

• Length: 319 a.a.
• Molecular weight: 36766.44 Da
• Isoelectric Point: 10.4054

>NTDB_id=1066919 ACH6FJ_RS05945 WP_002852903.1 1124312..1125271(+) (waaF) [Campylobacter jejuni strain YH018]
MKIFIHLPTWLGDAVMASPALYTIKEHFKNAQFILYGSLVSTALFKEFPNSKIIIENKQSRYKQALSLRKKLGKIDFSFA
FRSAFSSKIILHILKTKQRYFFDKNKYKEEHQVLKYLYFIENSLSIKAHFKDLKLPFKLKFQNPLVLKNGKKILGLNPGA
SFGSAKRWDASYFAKVALNFSQSHEILIFGAGKAEQELCNEIYQILKEQNIKVKNLCNKTTIKTLCQNIAFCDLFITNDS
GPMHLSAVYKVKTVAIFGPTKFTQTSPWQNQNAKLVHLDLACMPCMQKICPLKHHKCMKDLKPQRVIEEARNLLKNPHL

Nucleotide

• Length: 960 bp

>NTDB_id=1066919 ACH6FJ_RS05945 WP_002852903.1 1124312..1125271(+) (waaF) [Campylobacter jejuni strain YH018]
ATGAAAATTTTTATACACCTTCCCACTTGGCTAGGCGATGCGGTGATGGCTTCACCTGCTTTATACACCATAAAAGAACA
TTTTAAAAATGCTCAGTTTATCCTTTATGGATCTTTGGTTTCCACAGCACTTTTTAAAGAATTTCCTAATTCTAAAATCA
TCATAGAAAATAAACAATCCCGCTATAAACAAGCCCTATCTTTACGCAAAAAACTTGGTAAAATCGATTTTAGCTTTGCT
TTTAGATCTGCGTTTTCTTCTAAGATTATCTTGCATATTCTTAAAACAAAACAAAGATATTTTTTTGACAAAAACAAGTA
CAAAGAAGAACATCAAGTTTTAAAATACCTTTATTTTATAGAAAACTCACTTAGTATAAAAGCTCATTTTAAAGACTTAA
AACTTCCCTTTAAGCTAAAATTTCAAAACCCTCTTGTCTTAAAAAATGGCAAAAAAATTCTAGGACTCAACCCTGGCGCA
AGCTTTGGAAGTGCAAAAAGATGGGATGCGAGTTATTTTGCTAAAGTGGCTTTAAATTTCAGCCAAAGTCATGAGATTTT
AATCTTTGGTGCAGGAAAAGCCGAACAAGAACTTTGTAATGAAATTTATCAAATTTTAAAAGAACAAAACATAAAAGTAA
AAAATCTTTGCAATAAAACCACCATCAAAACCCTTTGTCAAAATATCGCTTTTTGCGATCTTTTCATCACAAATGACAGT
GGTCCTATGCACCTAAGTGCGGTTTATAAGGTAAAAACCGTAGCTATTTTTGGCCCCACAAAATTTACCCAAACTTCACC
TTGGCAAAATCAAAACGCAAAATTAGTACACTTAGATCTAGCTTGTATGCCTTGTATGCAAAAAATCTGCCCTTTAAAAC
ACCACAAATGCATGAAAGATTTAAAGCCTCAAAGGGTTATAGAAGAAGCTAGAAATTTACTTAAAAACCCTCATCTATAA

Domains

Predicted by InterproScan.

• Glycosyltransferase family 9 (heptosyltransferase) (Glyco_transf_9) (96-294)

3D structure

• AlphaFold DB: A0A5Y6P8U5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
waaF	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	94.984	100	0.95