Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EN71_RS04060 Genome accession   NZ_CP007631
Coordinates   744971..745756 (+) Length   261 a.a.
NCBI ID   WP_000825428.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NGBS061     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 739971..750756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN71_RS11890 (EN72_04155) - 741089..741532 (+) 444 WP_001048166.1 hypothetical protein -
  EN71_RS11895 (EN72_04160) - 741617..741883 (+) 267 WP_001865676.1 hypothetical protein -
  EN71_RS11900 (EN72_04165) - 741984..742112 (+) 129 WP_000962057.1 hypothetical protein -
  EN71_RS11905 (EN72_04170) - 742121..742441 (+) 321 WP_001865677.1 hypothetical protein -
  EN71_RS04050 (EN72_04175) - 742538..743208 (+) 671 Protein_745 ATP-binding cassette domain-containing protein -
  EN71_RS04055 (EN72_04180) - 743265..744710 (-) 1446 WP_000750933.1 FAD/NAD(P)-binding protein -
  EN71_RS04060 (EN72_04185) endA 744971..745756 (+) 786 WP_000825428.1 DNA/RNA non-specific endonuclease Machinery gene
  EN71_RS04065 (EN72_04190) - 745834..746472 (-) 639 WP_000478533.1 VTT domain-containing protein -
  EN71_RS04070 (EN72_04195) - 746689..747345 (+) 657 WP_000121094.1 ATP-binding cassette domain-containing protein -
  EN71_RS04075 (EN72_04200) - 747342..748115 (+) 774 WP_000011926.1 ABC transporter permease -
  EN71_RS04080 (EN72_04205) - 748279..749097 (+) 819 WP_000601004.1 hypothetical protein -
  EN71_RS04085 (EN72_04210) - 749134..750018 (-) 885 WP_000354837.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 29424.90 Da        Isoelectric Point: 9.3026

>NTDB_id=106574 EN71_RS04060 WP_000825428.1 744971..745756(+) (endA) [Streptococcus agalactiae strain NGBS061]
MKRLHKLFITVIATLGMLGVMTFGLPTQPKNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=106574 EN71_RS04060 WP_000825428.1 744971..745756(+) (endA) [Streptococcus agalactiae strain NGBS061]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGAAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(77-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

51.515

75.862

0.391
  endA Streptococcus pneumoniae D39

51.515

75.862

0.391
  endA Streptococcus pneumoniae R6

51.515

75.862

0.391
  endA Streptococcus pneumoniae TIGR4

51.515

75.862

0.391

Multiple sequence alignment