Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   EG66_RS05325 Genome accession   NZ_CP007605
Coordinates   1090012..1090890 (+) Length   292 a.a.
NCBI ID   WP_023592290.1    Uniprot ID   -
Organism   Helicobacter pylori strain BM012B     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1085012..1095890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EG66_RS05305 (EG66_05635) - 1085871..1087187 (+) 1317 WP_264356360.1 MATE family efflux transporter -
  EG66_RS05310 (EG66_05640) rny 1087188..1088699 (-) 1512 WP_023592287.1 ribonuclease Y -
  EG66_RS05315 (EG66_05645) - 1088677..1089351 (-) 675 WP_080261085.1 5-formyltetrahydrofolate cyclo-ligase -
  EG66_RS05320 (EG66_05650) - 1089449..1090006 (+) 558 WP_038420025.1 hypothetical protein -
  EG66_RS05325 (EG66_05655) pilA 1090012..1090890 (+) 879 WP_023592290.1 signal recognition particle-docking protein FtsY Machinery gene
  EG66_RS05330 (EG66_05660) - 1090899..1091213 (-) 315 WP_038420027.1 YkgJ family cysteine cluster protein -
  EG66_RS05335 - 1091272..1091997 (-) 726 Protein_1020 sortase -
  EG66_RS09040 - 1092171..1092425 (-) 255 Protein_1021 glycine zipper family protein -
  EG66_RS08460 (EG66_05670) - 1092437..1093986 (-) 1550 Protein_1022 DUF456 domain-containing protein -
  EG66_RS05350 (EG66_05680) moaA 1094232..1095197 (-) 966 WP_038420031.1 GTP 3',8-cyclase MoaA -
  EG66_RS05355 (EG66_05685) mobA 1095284..1095889 (+) 606 WP_038420033.1 molybdenum cofactor guanylyltransferase MobA -

Sequence

Protein


Download         Length: 292 a.a.        Molecular weight: 32599.85 Da        Isoelectric Point: 7.4169

>NTDB_id=106475 EG66_RS05325 WP_023592290.1 1090012..1090890(+) (pilA) [Helicobacter pylori strain BM012B]
MFNFFKKIVNKIKGEEKEKKRENIPKEELEEILIGFDIQYDLIESLLKHLGDLVTPKQLEVALLRFVRGESYYDKTRLKT
ITTKPLVHLIVGVNGAGKTTTIAKLAKLSLKQHKKTLIGAGDTFRAAAVKQLQLWGEKLNIQVISTKEGSDPSSLAYNTI
ESAIAKNIDEVFIDTAGRLHNQTNLKNELSKIARTCSKVLKDAPFYKFLILDGTQGSSGLTQAKIFHETLALDGVIMTKL
DGTSKGGAILSVLYELKLPILYLGMGEKEDDLIAFDEERFIEDLVDAVFVEQ

Nucleotide


Download         Length: 879 bp        

>NTDB_id=106475 EG66_RS05325 WP_023592290.1 1090012..1090890(+) (pilA) [Helicobacter pylori strain BM012B]
ATGTTTAATTTTTTCAAAAAAATTGTCAATAAGATTAAGGGCGAAGAGAAAGAAAAAAAGCGTGAAAATATTCCTAAAGA
GGAATTAGAAGAAATTTTGATTGGCTTTGACATCCAATACGATTTGATAGAAAGCTTGTTAAAGCATTTGGGCGATTTGG
TTACGCCCAAGCAATTAGAAGTCGCTTTGTTGCGTTTTGTGCGTGGGGAAAGTTACTATGATAAAACCCGCCTAAAGACC
ATCACCACAAAACCCTTAGTGCACTTAATCGTGGGGGTTAATGGGGCGGGTAAAACCACAACGATCGCTAAATTAGCCAA
ACTCTCTTTAAAACAGCATAAAAAAACGCTTATTGGGGCAGGTGACACTTTTAGAGCGGCCGCAGTCAAACAGCTCCAAT
TATGGGGCGAAAAGCTTAACATTCAAGTCATTAGCACTAAAGAAGGGAGCGATCCAAGCTCTTTAGCTTATAACACCATA
GAAAGTGCGATCGCTAAAAATATAGATGAAGTTTTTATAGACACCGCCGGGAGGCTACACAACCAGACCAACCTTAAGAA
CGAGCTTTCTAAAATCGCGCGCACCTGCTCTAAAGTTTTAAAAGACGCCCCCTTTTATAAATTCCTTATTTTAGACGGCA
CGCAAGGGAGCTCTGGTCTCACTCAAGCCAAAATTTTCCATGAGACTTTGGCACTAGACGGCGTGATTATGACTAAGCTT
GATGGCACTTCTAAAGGCGGAGCGATTTTAAGCGTGCTGTATGAGTTGAAATTACCCATTCTTTATTTAGGAATGGGCGA
AAAAGAAGACGATTTGATCGCTTTTGATGAAGAACGCTTTATAGAAGACTTGGTTGATGCGGTGTTTGTGGAGCAATAA

Domains

Predicted by InterProScan.

SRP54-type protein, GTPase domain (SRP54)

(86-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

40.824

91.438

0.373

Multiple sequence alignment