Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACGLYC_RS14910 Genome accession   NZ_CP171691
Coordinates   3032386..3033030 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain K12     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3027386..3038030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGLYC_RS14875 (ACGLYC_14875) - 3028565..3028996 (+) 432 WP_032867187.1 Na(+)/H(+) antiporter subunit B -
  ACGLYC_RS14880 (ACGLYC_14880) - 3028996..3029337 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  ACGLYC_RS14885 (ACGLYC_14885) - 3029330..3030817 (+) 1488 WP_032867186.1 Na+/H+ antiporter subunit D -
  ACGLYC_RS14890 (ACGLYC_14890) - 3030823..3031299 (+) 477 WP_007408672.1 Na+/H+ antiporter subunit E -
  ACGLYC_RS14895 (ACGLYC_14895) - 3031299..3031583 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  ACGLYC_RS14900 (ACGLYC_14900) mnhG 3031567..3031941 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  ACGLYC_RS14905 (ACGLYC_14905) - 3031981..3032364 (-) 384 WP_007408674.1 hotdog fold thioesterase -
  ACGLYC_RS14910 (ACGLYC_14910) comA 3032386..3033030 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  ACGLYC_RS14915 (ACGLYC_14915) comP 3033111..3035411 (-) 2301 WP_032867184.1 histidine kinase Regulator
  ACGLYC_RS14920 (ACGLYC_14920) comX 3035425..3035598 (-) 174 WP_012118314.1 competence pheromone ComX -
  ACGLYC_RS14925 (ACGLYC_14925) - 3035567..3036427 (-) 861 WP_157774448.1 polyprenyl synthetase family protein -
  ACGLYC_RS14930 (ACGLYC_14930) degQ 3036635..3036775 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACGLYC_RS14935 (ACGLYC_14935) - 3037241..3037582 (+) 342 WP_007408677.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=1063396 ACGLYC_RS14910 WP_003152052.1 3032386..3033030(-) (comA) [Bacillus velezensis strain K12]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1063396 ACGLYC_RS14910 WP_003152052.1 3032386..3033030(-) (comA) [Bacillus velezensis strain K12]
ATGAAAAAGATACTAGTGATTGATGATCATCCAGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCTAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCAATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment