Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACGLYC_RS06090 Genome accession   NZ_CP171691
Coordinates   1162961..1163617 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain K12     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1157961..1168617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGLYC_RS06065 (ACGLYC_06065) oppF 1158490..1159407 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACGLYC_RS06070 (ACGLYC_06070) - 1159514..1160701 (+) 1188 WP_032866147.1 putative glycoside hydrolase -
  ACGLYC_RS06075 (ACGLYC_06075) - 1160819..1161397 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ACGLYC_RS06080 (ACGLYC_06080) spx 1161576..1161971 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  ACGLYC_RS06085 (ACGLYC_06085) - 1162029..1162685 (-) 657 WP_032866146.1 TerC family protein -
  ACGLYC_RS06090 (ACGLYC_06090) mecA 1162961..1163617 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACGLYC_RS06095 (ACGLYC_06095) - 1163768..1164928 (+) 1161 WP_032866145.1 competence protein CoiA family protein -
  ACGLYC_RS06100 (ACGLYC_06100) pepF 1165156..1166985 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  ACGLYC_RS06105 (ACGLYC_06105) - 1167023..1167190 (-) 168 WP_003155026.1 hypothetical protein -
  ACGLYC_RS06110 (ACGLYC_06110) spxH 1167476..1168378 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1063361 ACGLYC_RS06090 WP_003155032.1 1162961..1163617(+) (mecA) [Bacillus velezensis strain K12]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1063361 ACGLYC_RS06090 WP_003155032.1 1162961..1163617(+) (mecA) [Bacillus velezensis strain K12]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment