Detailed information    

insolico Bioinformatically predicted

Overview

Name   cqsA   Type   Regulator
Locus tag   ACG4IV_RS18000 Genome accession   NZ_CP171689
Coordinates   974690..975859 (-) Length   389 a.a.
NCBI ID   WP_001039912.1    Uniprot ID   Q9KM65
Organism   Vibrio cholerae strain M647     
Function   induction of competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 969690..980859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG4IV_RS17995 cqsS 972401..974461 (+) 2061 WP_001882375.1 quorum-sensing CAI-1 autoinducer sensor kinase/phosphatase CqsS Regulator
  ACG4IV_RS18000 cqsA 974690..975859 (-) 1170 WP_001039912.1 alpha-hydroxyketone-type quorum-sensing autoinducer synthase Regulator
  ACG4IV_RS18005 - 976056..977018 (-) 963 WP_001104009.1 TDT family transporter -
  ACG4IV_RS18010 clcA 977165..978571 (-) 1407 WP_000107451.1 H(+)/Cl(-) exchange transporter ClcA -
  ACG4IV_RS18015 - 979038..980027 (+) 990 WP_000610709.1 GTP-binding protein -

Sequence

Protein


Download         Length: 389 a.a.        Molecular weight: 43593.61 Da        Isoelectric Point: 6.2272

>NTDB_id=1063328 ACG4IV_RS18000 WP_001039912.1 974690..975859(-) (cqsA) [Vibrio cholerae strain M647]
MNKPQLPDFIQNKIDHYIENYFDINKNGKHLVLGKQASPDDIILQSNDYLALANHPLIKARLAKSLLEEQQSLFMSASFL
QNDYDKPMIEKRLAKFTGFDECLLSQSGWNANVGLLQTICQPNTNVYIDFFAHMSLWEGARYANAQAHPFMHNNCDHLRM
LIQRHGPGIIVVDSIYSTLGTIAPLAELVNISKEFGCALLVDESHSLGTHGPNGAGLLAELGLTREVHFMTASLAKTFAY
RAGAIWCNNEVNRCVPFISYPAIFSSTLLPYEAAGLETTLEIIESADNRRQHLDRMARKLRIGLSQLGLTIRSESQIIGL
ETGDERNTEKVRDYLESNGVFGSVFCRPATSKNKNIIRLSLNSDVNDEQIAKIIEVCSDAVNYGDFYFR

Nucleotide


Download         Length: 1170 bp        

>NTDB_id=1063328 ACG4IV_RS18000 WP_001039912.1 974690..975859(-) (cqsA) [Vibrio cholerae strain M647]
ATGAACAAGCCTCAACTTCCTGATTTTATTCAGAACAAGATAGATCACTATATTGAAAATTATTTTGATATAAACAAAAA
CGGTAAACACCTTGTATTGGGTAAACAAGCCAGCCCTGATGACATTATTTTGCAAAGTAATGATTATCTCGCATTGGCCA
ATCATCCGTTGATCAAAGCTCGTTTGGCGAAGTCATTACTGGAAGAACAACAAAGCTTATTTATGTCAGCCTCATTTCTA
CAAAATGACTATGACAAACCCATGATTGAGAAACGTCTGGCTAAGTTCACAGGCTTTGATGAATGTCTATTATCTCAATC
TGGTTGGAATGCAAACGTCGGTTTATTACAAACCATCTGCCAGCCCAATACGAATGTTTACATTGATTTTTTCGCGCACA
TGTCGTTATGGGAAGGGGCGCGCTACGCCAATGCTCAGGCGCATCCTTTTATGCATAATAACTGTGACCATTTACGTATG
CTGATTCAACGTCATGGTCCTGGGATCATTGTCGTAGACTCGATTTACAGCACTTTAGGTACGATTGCACCGCTAGCGGA
ACTGGTCAATATCAGTAAAGAGTTTGGCTGCGCCTTATTAGTCGATGAATCCCACTCTTTGGGCACACATGGCCCTAATG
GTGCAGGTTTATTGGCAGAATTAGGCCTCACTCGTGAAGTGCATTTTATGACCGCAAGTTTGGCCAAAACCTTTGCTTAT
CGCGCAGGAGCCATTTGGTGTAACAATGAAGTGAATCGCTGCGTTCCTTTTATTAGTTATCCAGCTATTTTTAGTTCTAC
TTTGCTGCCTTATGAAGCGGCAGGATTAGAAACGACTTTAGAGATTATTGAATCTGCGGATAATCGTCGTCAGCATTTAG
ATCGTATGGCAAGAAAATTACGCATAGGATTATCCCAGCTGGGATTAACCATTCGCAGTGAAAGCCAAATTATTGGTCTA
GAAACAGGAGATGAACGAAATACCGAAAAAGTTCGGGATTATTTAGAAAGTAATGGAGTGTTTGGCTCAGTATTCTGCCG
CCCGGCAACTTCAAAGAATAAAAACATTATTCGCTTATCACTCAATAGTGATGTGAACGATGAGCAAATCGCCAAAATAA
TTGAGGTTTGCTCTGATGCGGTCAACTACGGTGATTTTTATTTTCGTTAA

Domains

Predicted by InterproScan.

Aminotransferase class I and II (Aminotran_1_2)

(41-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2WK7
  PDB 2WK8
  PDB 2WK9
  PDB 2WKA
  PDB 3HQT
  PDB 3KKI

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cqsA Vibrio cholerae strain A1552

100

100

1

Multiple sequence alignment