Detailed information NTG0106211

Bioinformatically predicted

Overview

• Name: treR
• Type: Regulator
• Locus tag: AAA996_RS08820
• Genome accession: NZ_AP028606
• Coordinates: 1736415..1737125 (+)
• Length: 236 a.a.
• NCBI ID: WP_000760673.1
• Uniprot ID: A0A062WVH4
• Organism: Streptococcus pneumoniae strain Sep1
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1737280..1738606	1736415..1737125	flank	155

Gene organization within MGE regions

Location: 1736415..1738606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA996_RS08820 (TKY121773_17470)	treR	1736415..1737125 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
AAA996_RS08825	-	1737280..1738606 (+)	1327	Protein_1747	ISL3 family transposase	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27607.78 Da
• Isoelectric Point: 8.9698

>NTDB_id=106211 AAA996_RS08820 WP_000760673.1 1736415..1737125(+) (treR) [Streptococcus pneumoniae strain Sep1]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide

• Length: 711 bp

>NTDB_id=106211 AAA996_RS08820 WP_000760673.1 1736415..1737125(+) (treR) [Streptococcus pneumoniae strain Sep1]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACAGACTATCTGGATATGGAACTAATTCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAAAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, gntR family (GntR) (3-66)

• UTRA domain (UTRA) (89-227)

3D structure

• AlphaFold DB: A0A062WVH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
treR	Streptococcus mutans UA159	59.322	100	0.593