Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   ACF8KG_RS11175 Genome accession   NZ_CP171532
Coordinates   2365547..2366143 (+) Length   198 a.a.
NCBI ID   WP_004179217.1    Uniprot ID   A0A085DH59
Organism   Klebsiella pneumoniae strain KP23_UID2108280019     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2363975..2365195 2365547..2366143 flank 352


Gene organization within MGE regions


Location: 2363975..2366143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF8KG_RS11170 - 2363975..2365195 (+) 1221 WP_000343760.1 ISL3-like element ISKox3 family transposase -
  ACF8KG_RS11175 sxy/tfoX 2365547..2366143 (+) 597 WP_004179217.1 TfoX/Sxy family DNA transformation protein Regulator

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 22516.11 Da        Isoelectric Point: 10.0350

>NTDB_id=1061881 ACF8KG_RS11175 WP_004179217.1 2365547..2366143(+) (sxy/tfoX) [Klebsiella pneumoniae strain KP23_UID2108280019]
MRKLVCPRLPQFQACVSPLGQLHTRPLFGGYSLAIDDTVFAMVAEGNIYLKACEQSAAYRVEHRNPLLTLRRHGRIVPLK
YYQIDDTLWRDEQQLFRLSLLSWQSAQREKNCRRASGRLKDLPNISFHMELQLIHAGIPDVRTLREVGAQEAWLRLRVNN
ASLSLSVLLALEGAIAGVHAAALPTPRRQELLEWAATR

Nucleotide


Download         Length: 597 bp        

>NTDB_id=1061881 ACF8KG_RS11175 WP_004179217.1 2365547..2366143(+) (sxy/tfoX) [Klebsiella pneumoniae strain KP23_UID2108280019]
ATGAGAAAACTAGTTTGTCCGCGGCTCCCGCAATTTCAGGCCTGCGTCTCACCGCTGGGTCAACTGCATACTCGTCCGCT
CTTTGGCGGCTACAGCCTGGCTATTGATGATACGGTGTTTGCGATGGTGGCCGAGGGAAACATTTATCTGAAGGCCTGCG
AGCAGAGCGCTGCTTATCGGGTGGAACATCGTAATCCTCTGTTAACGCTGCGCCGACACGGCCGCATAGTGCCGCTGAAG
TATTATCAAATTGACGACACTTTATGGCGCGATGAGCAGCAGCTTTTTCGGCTATCGCTACTGTCGTGGCAGAGTGCGCA
GCGCGAAAAGAACTGCCGACGGGCGTCGGGCCGCCTGAAGGATTTACCCAATATCAGCTTTCATATGGAATTGCAGCTGA
TTCACGCGGGCATACCGGACGTTAGGACGTTGCGGGAAGTTGGTGCGCAGGAGGCATGGCTGAGGCTACGCGTAAATAAT
GCTTCTTTATCGCTGAGCGTATTGCTGGCGCTGGAGGGGGCGATTGCCGGGGTACATGCCGCCGCGCTCCCGACGCCACG
GCGTCAGGAGCTTCTCGAATGGGCGGCTACCCGGTAG

Domains

Predicted by InterproScan.

TfoX C-terminal domain (TfoX_C)

(117-194)

TfoX N-terminal domain (TfoX_N)

(16-105)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A085DH59

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Escherichia coli BW25113 strain K-12

51.269

99.495

0.51

Multiple sequence alignment