Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACF0HW_RS12585 Genome accession   NZ_CP171208
Coordinates   2584077..2584733 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens strain HN11     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2579077..2589733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF0HW_RS12565 spxH 2579316..2580218 (+) 903 WP_012117287.1 protease adaptor protein SpxH -
  ACF0HW_RS12570 - 2580504..2580671 (+) 168 WP_003155026.1 hypothetical protein -
  ACF0HW_RS12575 pepF 2580709..2582538 (-) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  ACF0HW_RS12580 - 2582766..2583926 (-) 1161 WP_012117286.1 competence protein CoiA family protein -
  ACF0HW_RS12585 mecA 2584077..2584733 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACF0HW_RS12590 - 2584716..2584826 (-) 111 Protein_2482 adaptor protein MecA -
  ACF0HW_RS12595 - 2585009..2585665 (+) 657 WP_012117285.1 TerC family protein -
  ACF0HW_RS12600 spx 2585723..2586118 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  ACF0HW_RS12605 - 2586297..2586875 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ACF0HW_RS12610 - 2586984..2588180 (-) 1197 WP_012117284.1 putative glycoside hydrolase -
  ACF0HW_RS12615 oppF 2588287..2589204 (-) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1060493 ACF0HW_RS12585 WP_003155032.1 2584077..2584733(-) (mecA) [Bacillus amyloliquefaciens strain HN11]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1060493 ACF0HW_RS12585 WP_003155032.1 2584077..2584733(-) (mecA) [Bacillus amyloliquefaciens strain HN11]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
GGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment