Detailed information NTG0106044

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DX05_RS06850
• Genome accession: NZ_CP007572
• Coordinates: 1359708..1361816 (+)
• Length: 702 a.a.
• NCBI ID: WP_000002804.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain GBS6
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1354708..1366816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DX05_RS06840 (DX05_06965)	rplL	1358345..1358710 (-)	366	WP_001196976.1	50S ribosomal protein L7/L12	-
DX05_RS06845 (DX05_06970)	rplJ	1358774..1359274 (-)	501	WP_001287285.1	50S ribosomal protein L10	-
DX05_RS06850 (DX05_06975)	clpC	1359708..1361816 (+)	2109	WP_000002804.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DX05_RS06855 (DX05_06980)	mmuM	1361910..1362854 (-)	945	WP_000532330.1	homocysteine S-methyltransferase	-
DX05_RS06860 (DX05_06985)	-	1362859..1364235 (-)	1377	Protein_1282	amino acid permease	-
DX05_RS06865 (DX05_06990)	-	1364365..1365015 (-)	651	WP_000120090.1	HXXEE domain-containing protein	-
DX05_RS12230 (DX05_06995)	-	1365173..1365496 (-)	324	WP_001867206.1	HXXEE domain-containing protein	-
DX05_RS12340	-	1365548..1365676 (-)	129	WP_000854047.1	hypothetical protein	-
DX05_RS06875 (DX05_07000)	-	1365768..1366397 (+)	630	WP_000140673.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77675.45 Da
• Isoelectric Point: 4.8408

>NTDB_id=106044 DX05_RS06850 WP_000002804.1 1359708..1361816(+) (clpC) [Streptococcus agalactiae strain GBS6]
MANNNFYNRDPFGNMDDIFNSLMGNMGGYNSENKRYLINGREVTPEEFSQYRQTGKLPGQELNNQNTPTNQVSADSVLTK
LGTNLTDQARQHLLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIINGDVPAAIKNKEIISIDIS
SLEAGTQYRGSFEENIQNIIKEVKETGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAQDTFNILMGIRNLYEQHHNVVLPDSVLKAAVDLSIQYIPQRSLPDKAIDLIDMTAAHL
AAQHPVTDLKSLEKEIAAQRDKQEKAVNTEDFEEALKVKTRIEELQNQIDNHTEGQKVTATINDIAMSIERLTGVPVSNM
GASDIERLKELGNRLKGKVIGQNDAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAFDMFGSKDAIVR
LDMSEYNDRTAVSKLIGATAGYVGYDDNSNTLTERIRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFK
NTVIIATSNAGFGNEAFTGDSDKDLKIMERISPYFRPEFLNRFNGVIEFSHLSKDDLNEIVDLMLDEVNQTIGKKGIDLV
VDENVKSHLIDLGYDEAMGVRPLRRVIEQEIRDRITDYYLDHTDVKHLKANLQDGQIVISER

Nucleotide

• Length: 2109 bp

>NTDB_id=106044 DX05_RS06850 WP_000002804.1 1359708..1361816(+) (clpC) [Streptococcus agalactiae strain GBS6]
ATGGCAAATAATAATTTTTATAATCGTGACCCTTTTGGAAATATGGATGATATTTTTAATTCTCTAATGGGAAATATGGG
GGGCTATAATAGTGAGAATAAACGATACTTAATCAATGGACGGGAAGTTACTCCTGAAGAATTCAGTCAATATCGTCAAA
CTGGAAAACTCCCCGGTCAAGAGCTAAATAACCAAAATACTCCTACAAACCAAGTCTCTGCAGATAGTGTTTTGACTAAA
TTAGGAACTAATTTAACCGATCAAGCACGTCAGCATTTGCTAGATCCAGTTATTGGACGAAACAAAGAAATTCAGGAAAC
TGCAGAAATTCTAGCTCGTCGTACTAAAAATAATCCTGTTCTAGTTGGTGATGCAGGTGTTGGTAAAACAGCTGTTATTG
AAGGTTTGGCACAAGCAATTATAAATGGTGATGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCGATAGATATCTCT
AGCCTTGAAGCTGGCACCCAATATAGGGGTAGTTTTGAAGAAAATATTCAAAATATCATAAAAGAAGTTAAGGAAACAGG
AAATATTATTCTCTTCTTTGATGAAATACACCAAATATTAGGAGCCGGTTCAACTGGTGGTGATAGTGGCTCTAAGGGGC
TCGCAGATATACTTAAGCCTGCACTTTCACGTGGTGAATTAACGGTTATAGGTGCAACTACTCAAGATGAATATCGTAAC
ACCATTCTCAAGAATGCTGCCTTAGCACGCCGCTTTAACGAAGTTAAAGTCAATGCACCTTCTGCACAAGATACTTTCAA
TATCCTTATGGGGATAAGAAACCTCTATGAGCAACATCATAATGTTGTTTTACCTGACTCTGTTTTGAAAGCAGCTGTAG
ATTTATCTATTCAATACATACCACAAAGAAGTCTCCCTGATAAAGCAATTGACCTTATTGATATGACTGCTGCACACCTA
GCTGCGCAACATCCCGTAACTGACCTTAAATCCTTAGAAAAAGAAATCGCTGCGCAAAGAGACAAGCAAGAAAAAGCTGT
CAATACTGAAGATTTTGAAGAAGCTCTTAAGGTCAAGACACGCATTGAAGAGTTACAAAACCAGATTGATAATCATACCG
AAGGACAAAAAGTCACTGCAACTATCAATGATATCGCTATGTCAATTGAGCGTCTAACTGGAGTTCCTGTATCAAATATG
GGTGCTAGTGATATTGAACGCTTAAAAGAACTTGGCAATCGTCTAAAAGGTAAAGTCATTGGTCAAAATGATGCTGTTGA
GGCAGTTGCAAGAGCTATTCGCCGAAATCGTGCTGGTTTCGATGATGGTAATCGTCCGATTGGTAGCTTTCTATTTGTTG
GACCAACTGGAGTTGGTAAAACTGAGCTAGCAAAGCAATTAGCTTTTGATATGTTCGGATCAAAGGATGCTATCGTTAGA
CTTGATATGTCTGAATATAATGATCGTACTGCAGTTTCTAAGCTAATTGGAGCGACTGCTGGTTACGTTGGTTATGACGA
CAATAGTAATACACTAACAGAACGTATCCGTCGAAATCCTTATTCTATTGTTCTTCTTGATGAAATCGAAAAAGCTGACC
CGCAAGTTATCACGCTTCTCCTTCAAGTTCTAGATGATGGTCGTTTAACTGATGGTCAAGGAAACACTATTAACTTTAAA
AATACTGTTATCATTGCAACCTCAAATGCAGGTTTTGGAAACGAAGCATTTACAGGTGACAGCGATAAAGACTTGAAAAT
TATGGAACGAATTTCTCCATATTTCCGTCCAGAATTTCTAAATCGTTTCAATGGTGTTATTGAATTCTCTCACCTAAGCA
AAGATGACTTAAACGAAATTGTAGATTTGATGCTTGATGAAGTTAACCAAACAATTGGCAAAAAAGGAATTGACCTTGTG
GTAGATGAAAATGTTAAATCACACTTAATTGACCTGGGTTATGACGAAGCAATGGGAGTACGTCCATTGCGCCGTGTCAT
CGAGCAAGAAATTCGAGATCGCATCACAGACTACTATCTCGATCATACAGATGTTAAACACCTAAAAGCTAATTTGCAAG
ATGGCCAAATCGTCATTTCTGAAAGATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (261-358)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (612-683)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-252)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-604)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.489	99.288	0.472
clpE	Streptococcus pneumoniae TIGR4	48.983	91.026	0.446
clpE	Streptococcus pneumoniae Rx1	48.983	91.026	0.446
clpE	Streptococcus pneumoniae D39	48.983	91.026	0.446
clpE	Streptococcus pneumoniae R6	48.983	91.026	0.446
clpE	Streptococcus mutans UA159	49.367	90.028	0.444
clpC	Bacillus subtilis subsp. subtilis str. 168	44.03	95.442	0.42
clpC	Streptococcus pneumoniae Rx1	42.994	89.459	0.385
clpC	Streptococcus pneumoniae D39	42.994	89.459	0.385
clpC	Streptococcus pneumoniae TIGR4	42.994	89.459	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.706	90.171	0.376
clpC	Streptococcus thermophilus LMD-9	42.857	86.752	0.372
clpC	Streptococcus thermophilus LMG 18311	42.693	86.752	0.37
clpC	Streptococcus mutans UA159	40.566	90.598	0.368