Detailed information NTG1060226

Bioinformatically predicted

Overview

• Name: agrA
• Type: Regulator
• Locus tag: ACF3N8_RS05675
• Genome accession: NZ_CP171119
• Coordinates: 1191429..1192145 (-)
• Length: 238 a.a.
• NCBI ID: WP_009384258.1
• Uniprot ID: K9AK61
• Organism: Staphylococcus massiliensis strain WGS1515
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1186429..1197145

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF3N8_RS05655 (ACF3N8_05655)	-	1187302..1187958 (+)	657	WP_238101017.1	redox-sensing transcriptional repressor Rex	-
ACF3N8_RS05660 (ACF3N8_05660)	-	1188090..1189178 (+)	1089	WP_009384264.1	YeeE/YedE family protein	-
ACF3N8_RS05665 (ACF3N8_05665)	-	1189193..1189417 (+)	225	WP_009384262.1	sulfurtransferase TusA family protein	-
ACF3N8_RS05670 (ACF3N8_05670)	-	1189892..1191385 (+)	1494	WP_238101034.1	GH32 C-terminal domain-containing protein	-
ACF3N8_RS05675 (ACF3N8_05675)	agrA	1191429..1192145 (-)	717	WP_009384258.1	quorum-sensing response regulator AgrA	Regulator
ACF3N8_RS05680 (ACF3N8_05680)	agrC	1192158..1193450 (-)	1293	WP_026049014.1	quorum-sensing sensor histidine kinase AgrC	-
ACF3N8_RS05685 (ACF3N8_05685)	agrD	1193475..1193615 (-)	141	WP_009384253.1	cyclic lactone autoinducer peptide AgrD	-
ACF3N8_RS05690 (ACF3N8_05690)	-	1193618..1194187 (-)	570	WP_238101019.1	accessory gene regulator AgrB	-
ACF3N8_RS05695 (ACF3N8_05695)	-	1194669..1194746 (+)	78	WP_100223791.1	delta-lysin family phenol-soluble modulin	-
ACF3N8_RS05700 (ACF3N8_05700)	-	1194804..1194881 (+)	78	WP_009384249.1	delta-lysin family phenol-soluble modulin	-
ACF3N8_RS05705 (ACF3N8_05705)	-	1194938..1195015 (+)	78	WP_142382114.1	delta-lysin family phenol-soluble modulin	-
ACF3N8_RS05710 (ACF3N8_05710)	-	1195072..1195149 (+)	78	WP_142382114.1	delta-lysin family phenol-soluble modulin	-
ACF3N8_RS05715 (ACF3N8_05715)	-	1195205..1195282 (+)	78	WP_142382114.1	delta-lysin family phenol-soluble modulin	-
ACF3N8_RS05720 (ACF3N8_05720)	-	1195680..1196459 (-)	780	WP_017176855.1	carbon-nitrogen family hydrolase	-

Sequence

Protein

• Length: 238 a.a.
• Molecular weight: 28165.02 Da
• Isoelectric Point: 4.8117

>NTDB_id=1060226 ACF3N8_RS05675 WP_009384258.1 1191429..1192145(-) (agrA) [Staphylococcus massiliensis strain WGS1515]
MKILICEDDERQRERMVSIIENYIMIEDKPMEIEIATNDPYELLEHSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
IGNIVFVTSHSELTYLTFVYKVSAMDFIFKDDIDELKTRVIDCIETAHSRLDLLSKESNVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQLEFYGNLKELAQIDDRFFRCHNSFVLNRNNIERIDSKERIVYFKNEEYCYASVRNIKKI

Nucleotide

• Length: 717 bp

>NTDB_id=1060226 ACF3N8_RS05675 WP_009384258.1 1191429..1192145(-) (agrA) [Staphylococcus massiliensis strain WGS1515]
ATGAAAATTTTAATTTGTGAAGATGATGAGCGTCAACGTGAACGCATGGTTTCAATCATTGAGAATTACATCATGATTGA
AGATAAACCTATGGAAATCGAAATTGCCACAAATGATCCTTACGAGTTACTCGAACACTCTAAAAACATGACTGATATTG
GATGTTACTTTTTAGACATTCAACTCGAATCAGATATTAATGGAATAAAATTAGGTAGCGAGATCCGTAAACATGACCCA
ATTGGCAACATCGTATTTGTTACAAGTCATAGTGAGCTCACGTATCTCACTTTCGTTTATAAGGTTTCAGCAATGGACTT
TATTTTCAAAGATGATATTGATGAACTTAAGACGCGTGTTATAGATTGTATCGAAACTGCACACTCTCGATTAGACTTAT
TATCTAAAGAAAGTAACGTTGAAACAATTGAATTAAAACGCGGCAGTAATTCAGTATATGTGCAATATGACGATATTATG
TTCTTTGAATCATCAACCAAATCACATCGTTTAATTGCTCACTTAGACAATCGTCAACTTGAATTTTACGGTAATCTAAA
GGAACTCGCTCAAATCGATGACCGCTTCTTTAGATGCCATAACAGCTTCGTGCTTAACCGTAATAATATAGAACGTATTG
ATTCTAAAGAACGTATTGTCTACTTCAAGAACGAAGAATATTGTTACGCTTCGGTTCGTAACATCAAAAAAATATAG

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-237)

• Response regulator receiver domain (Response_reg) (3-120)

3D structure

• AlphaFold DB: K9AK61

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
agrA	Staphylococcus aureus N315	83.613	100	0.836