Detailed information NTG0105977

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: AAA985_RS09115
• Genome accession: NZ_AP028603
• Coordinates: 1749638..1750297 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565606.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Pne2
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1744638..1755297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA985_RS09090 (TKY181970_18030)	-	1744943..1745260 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
AAA985_RS09095 (TKY181970_18040)	-	1745275..1746171 (-)	897	WP_000825665.1	PEP phosphonomutase	-
AAA985_RS09100 (TKY181970_18050)	-	1746168..1747436 (-)	1269	WP_000413337.1	PTS sugar transporter subunit IIC	-
AAA985_RS09105 (TKY181970_18060)	-	1747716..1748894 (+)	1179	WP_000175879.1	ROK family transcriptional regulator	-
AAA985_RS09110 (TKY181970_18070)	-	1749122..1749568 (-)	447	WP_000155423.1	GNAT family N-acetyltransferase	-
AAA985_RS09115 (TKY181970_18080)	cclA/cilC	1749638..1750297 (+)	660	WP_000565606.1	A24 family peptidase	Machinery gene
AAA985_RS09120 (TKY181970_18090)	trpA	1750269..1751045 (-)	777	WP_001126993.1	tryptophan synthase subunit alpha	-
AAA985_RS09125 (TKY181970_18100)	trpB	1751038..1752261 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
AAA985_RS09130 (TKY181970_18110)	-	1752239..1752838 (-)	600	WP_000169872.1	phosphoribosylanthranilate isomerase	-
AAA985_RS09135 (TKY181970_18120)	trpC	1752825..1753592 (-)	768	WP_000076545.1	indole-3-glycerol phosphate synthase TrpC	-
AAA985_RS09140 (TKY181970_18130)	trpD	1753589..1754593 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
AAA985_RS09145 (TKY181970_18140)	-	1754604..1755170 (-)	567	WP_000601921.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24860.94 Da
• Isoelectric Point: 7.3241

>NTDB_id=105977 AAA985_RS09115 WP_000565606.1 1749638..1750297(+) (cclA/cilC) [Streptococcus pneumoniae strain Pne2]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLHPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLFYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=105977 AAA985_RS09115 WP_000565606.1 1749638..1750297(+) (cclA/cilC) [Streptococcus pneumoniae strain Pne2]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCATCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGTTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae Rx1	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae D39	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae R6	95.89	100	0.959
cclA/cilC	Streptococcus mitis SK321	92.694	100	0.927
cclA/cilC	Streptococcus mitis NCTC 12261	86.758	100	0.868