Detailed information NTG0105944

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AAA985_RS02125
• Genome accession: NZ_AP028603
• Coordinates: 378512..380614 (+)
• Length: 700 a.a.
• NCBI ID: WP_219600826.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Pne2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 373512..385614

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA985_RS02105 (TKY181970_04100)	rsmH	373655..374605 (+)	951	WP_000159397.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
AAA985_RS02110 (TKY181970_04110)	ftsL	374617..374934 (+)	318	WP_000818547.1	cell division protein FtsL	-
AAA985_RS02115 (TKY181970_04120)	pbp2X	374938..377190 (+)	2253	WP_219600824.1	penicillin-binding protein PBP2X	-
AAA985_RS02120 (TKY181970_04130)	mraY	377192..378172 (+)	981	WP_219600825.1	phospho-N-acetylmuramoyl-pentapeptide- transferase	-
AAA985_RS02125 (TKY181970_04140)	clpC	378512..380614 (+)	2103	WP_219600826.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
AAA985_RS02130 (TKY181970_04150)	-	381065..381400 (+)	336	Protein_418	group II intron maturase-specific domain-containing protein	-
AAA985_RS02135 (TKY181970_04160)	-	381467..381949 (-)	483	WP_000032551.1	S-ribosylhomocysteine lyase	-
AAA985_RS02140 (TKY181970_04170)	-	382044..383528 (-)	1485	WP_000743617.1	DUF1846 domain-containing protein	-
AAA985_RS02145 (TKY181970_04180)	-	383681..385288 (+)	1608	WP_001156802.1	alpha-glucosidase	-

Sequence

Protein

• Length: 700 a.a.
• Molecular weight: 77413.21 Da
• Isoelectric Point: 4.7361

>NTDB_id=105944 AAA985_RS02125 WP_219600826.1 378512..380614(+) (clpC) [Streptococcus pneumoniae strain Pne2]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAIYRQTGQLPSEGSEQVQYVQGKGMKQDGVLAKLGR
NLTAEAREGKLDPVIGRNKEIQEASEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLE
AGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTIL
KNAALARRFNEVKVNAPSAKDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQ
HPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGAS
DIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDM
SEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTV
IIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVSQ
AAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGGLVISEKA

Nucleotide

• Length: 2103 bp

>NTDB_id=105944 AAA985_RS02125 WP_219600826.1 378512..380614(+) (clpC) [Streptococcus pneumoniae strain Pne2]
ATGAACAACAATTTTAATAATTTTAACAACATGGATGATTTGTTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGTCGTTACTTGATTAACGGCCGTGAAGTAACGCCTGAAGAATTCGCTATTTACCGTCAAACTGGTCAACTTC
CAAGCGAAGGAAGTGAACAAGTTCAGTACGTTCAAGGTAAAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGTCGA
AACTTGACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAGCGTCTGAAAT
TCTTTCACGCCGTACCAAGAACAATCCTGTTTTGGTCGGAGACGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGCCTAG
CACAAGCTATTGTGAATGGTGATGTTCCAGCTGCTATTAAAAACAAGGAAATTATTTCTATTGATATCTCTGGTCTTGAG
GCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAACGTTCAAAACTTAGTCAATGAAGTCAAAGAAGCAGGGAATATTAT
TCTCTTCTTTGATGAAATTCACCAAATACTTGGTGCTGGTTCTACTGGAGGTGACAGTGGTTCTAAGGGGCTTGCGGATA
TTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACGACTCAAGATGAATACCGTAACACGATTTTG
AAGAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCAGCAAAGGATACTTTTAAAATTCTTCA
AGGAATTCGTGATCTCTATCAACAACACCACAATGTTATCTTGCCAGATGAAGTTTTGAAAGCAGCAGTGGATTATTCTG
TTCAGTATATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACAGCGGCTCACTTGGCAGCACAA
CATCCTGTAACAGATGTACATGCTGTTGAACGTGAAATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCTGTCGAGGCGGA
AGATTTTGAAGCAGCTCTAAACTATAAAACACGCATCGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATATGA
AAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTAGAACGAATGACCGGTATTCCAGTATCGCAAATGGGAGCTTCA
GATATCGAACGTTTGAAAGATATGGCTCATCGTCTGCAAGATAAGGTAATTGGCCAAGACAAGGCGGTAGAAGCGGTAGC
TCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGTCCTACTG
GTGTTGGTAAGACTGAGTTGGCTAAACAATTGGCTCTAGATATGTTCGGAACGAAAGATGCTATCATCCGTTTGGACATG
TCAGAATACAGCGACCGCACAGCCGTATCTAAATTGATTGGTACAACTGCAGGTTATGTTGGTTACGATGACAACAACAA
TACCTTGACAGAACGCGTCCGTCGCAATCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCA
TCACCCTTCTCCTTCAAGTTTTGGATGATGGTCGTTTGACAGATGGTCAGGGAAATACAGTAAACTTTAAAAACACTGTC
ATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGACAAACCAGAATTGATGGATCG
TTTGAAACCATTCTTCCGTCCAGAATTCCTTAACCGCTTCAACGCAGTTATCGAGTTCTCGCACTTGACTAAGGAAGACC
TTTCTAAGATTGTGGACTTGATGTTGGCTGAAGTCAACCAAACCTTGGCTAAGAAAGACATTGATTTGGTAGTCAGTCAA
GCGGCTAAGGATTATATTACAGAAGAAGGCTATGATGAAGTCATGGGTGTTCGTCCTCTCCGTCGCGTAGTTGAACAAGA
AATTCGTGATAAGGTGACAGACTTCCATTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGTGGTT
TGGTTATTAGTGAGAAAGCTTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (117-249)

• AAA lid domain (AAA_lid_9) (258-353)

• AAA domain (Cdc48 subfamily) (AAA_2) (442-602)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (609-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	48.006	100	0.481
clpE	Streptococcus mutans UA159	47.135	99.714	0.47
clpE	Streptococcus pneumoniae TIGR4	48.973	90.429	0.443
clpE	Streptococcus pneumoniae Rx1	48.973	90.429	0.443
clpE	Streptococcus pneumoniae D39	48.973	90.429	0.443
clpE	Streptococcus pneumoniae R6	48.973	90.429	0.443
clpC	Bacillus subtilis subsp. subtilis str. 168	45.146	92.714	0.419
clpC	Streptococcus pneumoniae Rx1	41.504	95	0.394
clpC	Streptococcus pneumoniae D39	41.504	95	0.394
clpC	Streptococcus pneumoniae TIGR4	41.353	95	0.393
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.436	88.143	0.383
clpC	Streptococcus thermophilus LMD-9	43.065	88.571	0.381
clpC	Streptococcus thermophilus LMG 18311	42.903	88.571	0.38
clpC	Streptococcus mutans UA159	42.071	88.286	0.371