Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   AABA08_RS10325 Genome accession   NZ_AP028602
Coordinates   2018536..2019198 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain PF2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2013536..2024198
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA08_RS10300 (TKY092604_19920) - 2013686..2013952 (-) 267 WP_001278167.1 Veg family protein -
  AABA08_RS10305 (TKY092604_19930) dnaB 2013954..2015306 (-) 1353 WP_000852481.1 replicative DNA helicase -
  AABA08_RS10310 (TKY092604_19940) rplI 2015350..2015802 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  AABA08_RS10315 (TKY092604_19950) - 2015799..2017772 (-) 1974 WP_000715109.1 DHH family phosphoesterase -
  AABA08_RS10320 (TKY092604_19960) hpf 2017908..2018456 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  AABA08_RS10325 (TKY092604_19970) comFC/cflB 2018536..2019198 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  AABA08_RS10330 (TKY092604_19980) comFA/cflA 2019195..2020493 (-) 1299 WP_000867588.1 DEAD/DEAH box helicase Machinery gene
  AABA08_RS10335 (TKY092604_19990) - 2020549..2021184 (+) 636 WP_000395739.1 YigZ family protein -
  AABA08_RS10340 (TKY092604_20000) cysK 2021469..2022395 (+) 927 WP_000029875.1 cysteine synthase A -
  AABA08_RS10345 (TKY092604_20010) tsf 2022517..2023557 (-) 1041 WP_000808068.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=105928 AABA08_RS10325 WP_000649971.1 2018536..2019198(-) (comFC/cflB) [Streptococcus pneumoniae strain PF2]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=105928 AABA08_RS10325 WP_000649971.1 2018536..2019198(-) (comFC/cflB) [Streptococcus pneumoniae strain PF2]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment