Detailed information NTG1059061

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: ACFWFW_RS25380
• Genome accession: NZ_CP170738
• Coordinates: 4851532..4852326 (+)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain Bundesheer
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4846532..4857326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFWFW_RS25365 (ACFWFW_25415)	argR	4847371..4847820 (+)	450	WP_001032581.1	arginine repressor ArgR	-
ACFWFW_RS25370 (ACFWFW_25420)	recN	4848088..4849827 (+)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
ACFWFW_RS25375 (ACFWFW_25425)	spoIVB	4849946..4851244 (+)	1299	WP_002037056.1	SpoIVB peptidase	-
ACFWFW_RS25380 (ACFWFW_25430)	spo0A	4851532..4852326 (+)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
ACFWFW_RS25385 (ACFWFW_25435)	-	4852624..4854150 (+)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
ACFWFW_RS25390 (ACFWFW_25440)	-	4854318..4854464 (-)	147	WP_001247671.1	YycC family protein	-
ACFWFW_RS25395 (ACFWFW_25445)	-	4854515..4855243 (+)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
ACFWFW_RS25400 (ACFWFW_25450)	-	4855292..4855525 (-)	234	WP_001190187.1	DUF2627 domain-containing protein	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=1059061 ACFWFW_RS25380 WP_003161566.1 4851532..4852326(+) (spo0A) [Bacillus anthracis strain Bundesheer]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=1059061 ACFWFW_RS25380 WP_003161566.1 4851532..4852326(+) (spo0A) [Bacillus anthracis strain Bundesheer]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818