Detailed information NTG0105899

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AABA08_RS08280
• Genome accession: NZ_AP028602
• Coordinates: 1648898..1649965 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159564.1
• Uniprot ID: A0A6I3U7F3
• Organism: Streptococcus pneumoniae strain PF2
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1643898..1654965

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA08_RS08265 (TKY092604_16410)	treR	1645687..1646397 (+)	711	WP_000760675.1	trehalose operon repressor	Regulator
AABA08_RS08270	-	1646552..1647886 (+)	1335	Protein_1638	ISL3 family transposase	-
AABA08_RS08275 (TKY092604_16440)	amiF	1647961..1648887 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
AABA08_RS08280 (TKY092604_16450)	amiE	1648898..1649965 (-)	1068	WP_000159564.1	ABC transporter ATP-binding protein	Regulator
AABA08_RS08285 (TKY092604_16460)	amiD	1649974..1650900 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
AABA08_RS08290 (TKY092604_16470)	amiC	1650900..1652396 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
AABA08_RS08295 (TKY092604_16480)	amiA3	1652463..1654442 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39520.11 Da
• Isoelectric Point: 4.8727

>NTDB_id=105899 AABA08_RS08280 WP_000159564.1 1648898..1649965(-) (amiE) [Streptococcus pneumoniae strain PF2]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRSQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=105899 AABA08_RS08280 WP_000159564.1 1648898..1649965(-) (amiE) [Streptococcus pneumoniae strain PF2]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTAGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A6I3U7F3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538