Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACFXAD_RS14925 Genome accession   NZ_CP170653
Coordinates   3051835..3052491 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens strain JP5011     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3046835..3057491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFXAD_RS14905 (ACFXAD_14905) spxH 3047073..3047975 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  ACFXAD_RS14910 (ACFXAD_14910) - 3048262..3048429 (+) 168 WP_003155026.1 hypothetical protein -
  ACFXAD_RS14915 (ACFXAD_14915) pepF 3048467..3050296 (-) 1830 WP_108702427.1 oligoendopeptidase F Regulator
  ACFXAD_RS14920 (ACFXAD_14920) - 3050524..3051684 (-) 1161 WP_053573556.1 competence protein CoiA family protein -
  ACFXAD_RS14925 (ACFXAD_14925) mecA 3051835..3052491 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACFXAD_RS14930 (ACFXAD_14930) - 3052767..3053423 (+) 657 WP_007409109.1 TerC family protein -
  ACFXAD_RS14935 (ACFXAD_14935) spx 3053480..3053875 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  ACFXAD_RS14940 (ACFXAD_14940) - 3054053..3054631 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ACFXAD_RS14945 (ACFXAD_14945) - 3054749..3055936 (-) 1188 WP_040238278.1 putative glycoside hydrolase -
  ACFXAD_RS14950 (ACFXAD_14950) oppF 3056043..3056960 (-) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1058510 ACFXAD_RS14925 WP_003155032.1 3051835..3052491(-) (mecA) [Bacillus amyloliquefaciens strain JP5011]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1058510 ACFXAD_RS14925 WP_003155032.1 3051835..3052491(-) (mecA) [Bacillus amyloliquefaciens strain JP5011]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment