Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACFXAB_RS16945 Genome accession   NZ_CP170650
Coordinates   3463530..3464186 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain JP5039     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3458530..3469186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFXAB_RS16925 (ACFXAB_16925) spxH 3458767..3459669 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  ACFXAB_RS16930 (ACFXAB_16930) - 3459956..3460123 (+) 168 WP_003155026.1 hypothetical protein -
  ACFXAB_RS16935 (ACFXAB_16935) pepF 3460161..3461990 (-) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  ACFXAB_RS16940 (ACFXAB_16940) - 3462218..3463378 (-) 1161 WP_014417422.1 competence protein CoiA family protein -
  ACFXAB_RS16945 (ACFXAB_16945) mecA 3463530..3464186 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACFXAB_RS16950 (ACFXAB_16950) - 3464462..3465118 (+) 657 WP_014417421.1 TerC family protein -
  ACFXAB_RS16955 (ACFXAB_16955) spx 3465175..3465570 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  ACFXAB_RS16960 (ACFXAB_16960) - 3465749..3466327 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ACFXAB_RS16965 (ACFXAB_16965) - 3466436..3467632 (-) 1197 WP_014417420.1 putative glycoside hydrolase -
  ACFXAB_RS16970 (ACFXAB_16970) oppF 3467739..3468656 (-) 918 WP_014417419.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1058364 ACFXAB_RS16945 WP_003155032.1 3463530..3464186(-) (mecA) [Bacillus velezensis strain JP5039]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1058364 ACFXAB_RS16945 WP_003155032.1 3463530..3464186(-) (mecA) [Bacillus velezensis strain JP5039]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCAAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment