Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOS_RS10060 Genome accession   NZ_CP170436
Coordinates   2035109..2035825 (+) Length   238 a.a.
NCBI ID   WP_410540787.1    Uniprot ID   -
Organism   Staphylococcus aureus strain t1510     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2030109..2040825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOS_RS10030 - 2030324..2030950 (+) 627 WP_000522375.1 nitroreductase family protein -
  ACFIOS_RS10035 - 2031311..2032096 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  ACFIOS_RS10040 hld 2032697..2032777 (-) 81 WP_000046022.1 delta-hemolysin -
  ACFIOS_RS10045 agrB 2033067..2033636 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACFIOS_RS10050 agrD 2033633..2033773 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOS_RS10055 agrC 2033798..2035090 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOS_RS10060 agrA 2035109..2035825 (+) 717 WP_410540787.1 quorum-sensing response regulator AgrA Regulator
  ACFIOS_RS10065 - 2035897..2036004 (+) 108 WP_031785433.1 hypothetical protein -
  ACFIOS_RS10070 - 2036194..2037153 (-) 960 WP_001253295.1 carbohydrate kinase family protein -
  ACFIOS_RS10075 - 2037150..2038634 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  ACFIOS_RS10080 - 2038783..2039733 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27891.87 Da        Isoelectric Point: 6.0927

>NTDB_id=1057375 ACFIOS_RS10060 WP_410540787.1 2035109..2035825(+) (agrA) [Staphylococcus aureus strain t1510]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEVALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1057375 ACFIOS_RS10060 WP_410540787.1 2035109..2035825(+) (agrA) [Staphylococcus aureus strain t1510]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAGTTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment