Detailed information NTG1057336

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ACFIOK_RS13510
• Genome accession: NZ_CP170434
• Coordinates: 2719200..2720549 (+)
• Length: 449 a.a.
• NCBI ID: WP_410540881.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain t315
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	2715626..2720549	2719200..2720549	within	0

Gene organization within MGE regions

Location: 2715626..2720549

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOK_RS13500	-	2715626..2717056 (+)	1431	WP_001008607.1	DUF6038 family protein	-
ACFIOK_RS13505	cch1	2717176..2718966 (+)	1791	WP_103449990.1	cassette chromosome replicative helicase	-
ACFIOK_RS13510	ccrA	2719200..2720549 (+)	1350	WP_410540881.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52627.33 Da
• Isoelectric Point: 10.0230

>NTDB_id=1057336 ACFIOK_RS13510 WP_410540881.1 2719200..2720549(+) (ccrA) [Staphylococcus aureus strain t315]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQSKPISSISAYQIQRAFQ
NIIQQRFTLNMLYPYIDQIHITKKKMLVGIYFKNEPLNIVNQTTQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=1057336 ACFIOK_RS13510 WP_410540881.1 2719200..2720549(+) (ccrA) [Staphylococcus aureus strain t315]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATTATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACGAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACGCAATCATTACGTCAGCAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCAAAGAGCGTTTCAA
AACATCATTCAACAACGTTTCACGCTAAACATGTTATACCCTTATATTGATCAAATTCATATCACAAAAAAGAAAATGCT
TGTTGGCATTTATTTCAAAAATGAACCCTTAAATATCGTCAATCAAACAACACAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Recombinase (Recombinase) (169-250)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	94.432	100	0.944
ccrA	Staphylococcus aureus COL	77.951	100	0.78