Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOD_RS03590 Genome accession   NZ_CP170429
Coordinates   720586..721302 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain t1531     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 715586..726302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOD_RS03570 - 716678..717628 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  ACFIOD_RS03575 - 717777..719261 (+) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  ACFIOD_RS03580 - 719258..720217 (+) 960 WP_001253312.1 carbohydrate kinase family protein -
  ACFIOD_RS03585 - 720405..720514 (-) 110 Protein_702 hypothetical protein -
  ACFIOD_RS03590 agrA 720586..721302 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACFIOD_RS03595 agrC 721321..722604 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOD_RS03600 agrD 722634..722777 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOD_RS03605 - 722780..723343 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  ACFIOD_RS03610 hld 723633..723713 (+) 81 WP_000046022.1 delta-hemolysin -
  ACFIOD_RS03615 - 724313..725098 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  ACFIOD_RS03620 - 725459..726085 (-) 627 WP_410540997.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1057218 ACFIOD_RS03590 WP_000688492.1 720586..721302(-) (agrA) [Staphylococcus aureus strain t1531]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1057218 ACFIOD_RS03590 WP_000688492.1 720586..721302(-) (agrA) [Staphylococcus aureus strain t1531]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment