Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOM_RS10785 Genome accession   NZ_CP170425
Coordinates   2145281..2145997 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain t197     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2140281..2150997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOM_RS10755 - 2140500..2141126 (+) 627 WP_000522384.1 nitroreductase family protein -
  ACFIOM_RS10760 - 2141487..2142272 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  ACFIOM_RS10765 hld 2142869..2142949 (-) 81 WP_000046022.1 delta-hemolysin -
  ACFIOM_RS10770 agrB 2143239..2143808 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  ACFIOM_RS10775 agrD 2143805..2143945 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOM_RS10780 agrC 2143970..2145262 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOM_RS10785 agrA 2145281..2145997 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACFIOM_RS10790 - 2146069..2146176 (+) 108 WP_001790167.1 hypothetical protein -
  ACFIOM_RS10795 - 2146364..2147323 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  ACFIOM_RS10800 - 2147320..2148804 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  ACFIOM_RS10805 - 2148953..2149903 (-) 951 WP_410531765.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1057163 ACFIOM_RS10785 WP_000688492.1 2145281..2145997(+) (agrA) [Staphylococcus aureus strain t197]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1057163 ACFIOM_RS10785 WP_000688492.1 2145281..2145997(+) (agrA) [Staphylococcus aureus strain t197]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment